Study to Evaluate the REMEDY SPECTRUM IM Spacer Nail in the Treatment of Ankle-Related Infections

Inclusion Criteria: 1. Be ≥ 21 years of age 2. Have an ankle-related infection 3. Is skeletally mature, as evidenced by closed epiphyses. 4. Be able to give voluntary, written informed consent to participate and have signed an Informed Consent Form specific to this study 5. Be willing and able to comply with all study procedures including all pre-operative, post-operative requirements 6. If female and of child-bearing potential, must have a negative pregnancy test prior to the surgical procedure and no intention of becoming pregnant until study completion. Exclusion Criteria: 1. Infections that do not involve the ankle 2. Have a known immunodeficiency; including subjects who are receiving or have received immunosuppressants, immunostimulating agents or radiation therapy within 6 months prior to surgery 3. Affected limb is dysvascular 4. Where adequate soft-tissue coverage cannot be achieved 5. Have any mental or psychological disorder that would impair their ability to complete the study questionnaires 6. Are currently pregnant or breastfeeding, or planning to become pregnant or breastfeed any time during the course of the study 7. Are currently a prisoner 8. Have any medical condition or other circumstances, in the judgment of the Investigator, that might interfere with the ability to return for follow-up visits, including any systemic illness, neuromuscular, neurosensory, or musculoskeletal deficiency that would render the subject unable to perform appropriate post-operative activities. 9. History of vancomycin or gentamicin allergy 10. Are implanted with other antibiotic eluting products.