Prior observational studies have shown that higher levels of vegetables and fruits consumption are associated with lower risk of all-cause mortality in patients with chronic kidney disease (CKD). However, compared with the normal population, patients with CKD are more likely to consume less vegetables and fruits. Thus, the investigators aim to evaluate whether proving low-potassium content vegetables to this population are able to reach the recommended target of daily vegetables intake and not increase the risk of hyperkalemia.
Prior observational studies have shown that higher levels of vegetables and fruits consumption are associated with lower risk of all-cause mortality in patients with chronic kidney disease (CKD). However, compared with the normal population, patients with CKD are more likely to consume less vegetables and fruits. According to the suggestions from 2018 Ministry of Health and Welfare in Taiwan, vegetables intake are at least 3 to 5 servings daily based on the daily energy requirement. In our own data, the average daily vegetables intake was only 2.1 servings among patients with CKD stages 3 to 5 not yet on dialysis. Therefore, the investigators aim to evaluate whether proving low-potassium content vegetables to patients with CKD stages 3 to 5 not yet on dialysis are able to reach the recommended target of daily vegetables intake and not increase the risk of hyperkalemia.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
NONE
Enrollment
75
low-potassium vegetables 3 to 5 serving according to their daily suggested requirement
Taipei Tzu Chi Hospital
New Taipei City, Taiwan
RECRUITINGTaipei Tzu Chi Hospital
New Taipei City, Taiwan
RECRUITINGPercentage of participants who reach the targets of daily vegetable recommended target
Percentage of participants who reach the targets of daily vegetable recommended
Time frame: 8 weeks
Gut-derived uremic toxins
Change in gut-derived uremic toxins ( indoxyl sulfate, p-cresyl sulfate)
Time frame: 8 weeks
Serum creatinine
Change in serum creatinine in mg/dL
Time frame: 8 weeks
Proteinuria
Change in proteinuria in g/day
Time frame: 8 weeks
Occurrence of moderate hyperkalemia
serum \[potassium\] \>=5.5 mmol/L
Time frame: 8 weeks
Status of constipation
Using the Chinese constipation questionnaire. The minimum value is 0, and the maximum value is 21, and the higher score represents a worse outcome.
Time frame: 8 weeks
Gut microbiome
Change in alpha- and beta-diversities indices
Time frame: 8 weeks
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