In this study, changes in new oxygenation indices investigated by Asar et al. will be compared with conventional oxygenation and saturation indices in patients undergoing robot-assisted laparoscopic surgery due to pneumoperitoneum and Trendelenburg position.
During the intraoperative period, optimal oxygenation should be achieved while avoiding the harmful effects of hypoxia and hyperoxia in patients. The PaO2/FiO2 and SpO2/FiO2 ratios have been traditionally used to assess this condition. Subsequently, oxygenation indices incorporating mean airway pressure have been developed, such as the oxygenation index (OI = (FiO2 × Pmean) / PaO2) and oxygenation saturation index (OSI = (FiO2 × Pmean) / SpO2). More recently, Asar et al. have defined 8 novel oxygenation indices using mean power (MP) and driving pressure (DP) instead of Pmean (OSI-MPtot, OI-MPtot, OSI-ΔPinsp, OI-ΔPinsp, OSI-MPdyn, OI-MPdyn, PaO2/(FiO2xPEEP), and SpO2/FiO2xPEEP). They compared the predictive power of these new indices for intensive care unit (ICU) mortality in COVID-ARDS (C-ARDS) patients with conventional oxygenation indices (PaO2/FiO2, SpO2/FiO2, OI, OSI). OI-ΔPinsp, OSI-ΔPinsp, and OSI-MPdyn indices were found to have the highest predictive power for ICU mortality. However, there is currently no study investigating the changes of these new indices during the intraoperative period.
Study Type
OBSERVATIONAL
Enrollment
56
Arterial blood gas was obtained immediately after intubation(Tint) in supine position. Ventilator parameters and hemodynamic parameters were recorded.
Arterial blood gas was obtained immediately after pneumoperitoneum in trendelenburg position. Ventilator parameters and hemodynamic parameters were recorded.
Arterial blood gas was obtained immediately after pneumoperitoneum in trendelenburg position. Ventilator parameters and hemodynamic parameters were recorded.
Basaksehir Cam Sakura City Hospital
Istanbul, Turkey (Türkiye)
Oxygenation indices
This study aims to investigate the effects of Trendelenburg position and pneumoperitoneum OSI-MPtot in ASA I-III patients undergoing robot-assisted laparoscopic surgery.
Time frame: during the surgery and immediately after the surgery (approximately 3 hours to 6 hours)
Oxygenation indices
This study aims to investigate the effects of Trendelenburg position and pneumoperitoneum on OI-MPtot in ASA I-III patients undergoing robot-assisted laparoscopic surgery.
Time frame: during the surgery and immediately after the surgery (approximately 3 hours to 6 hours)
Oxygenation indices
This study aims to investigate the effects of Trendelenburg position and pneumoperitoneum on OSI-ΔPinsp in ASA I-III patients undergoing robot-assisted laparoscopic surgery.
Time frame: during the surgery and immediately after the surgery (approximately 3 hours to 6 hours)
Oxygenation indices
This study aims to investigate the effects of Trendelenburg position and pneumoperitoneum on OI-ΔPinsp in ASA I-III patients undergoing robot-assisted laparoscopic surgery.
Time frame: during the surgery and immediately after the surgery (approximately 3 hours to 6 hours)
Oxygenation indices
This study aims to investigate the effects of Trendelenburg position and pneumoperitoneum on OSI-MPdyn in ASA I-III patients undergoing robot-assisted laparoscopic surgery.
Time frame: during the surgery and immediately after the surgery (approximately 3 hours to 6 hours)
Oxygenation indices
This study aims to investigate the effects of Trendelenburg position and pneumoperitoneum on OI-MPdyn in ASA I-III patients undergoing robot-assisted laparoscopic surgery.
Time frame: during the surgery and immediately after the surgery (approximately 3 hours to 6 hours)
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Oxygenation indices
This study aims to investigate the effects of Trendelenburg position and pneumoperitoneum on PaO2/(FiO2xPEEP) in ASA I-III patients undergoing robot-assisted laparoscopic surgery.
Time frame: during the surgery and immediately after the surgery (approximately 3 hours to 6 hours)
Oxygenation indices
This study aims to investigate the effects of Trendelenburg position and pneumoperitoneum on SpO2/FiO2xPEEP in ASA I-III patients undergoing robot-assisted laparoscopic surgery.
Time frame: during the surgery and immediately after the surgery (approximately 3 hours to 6 hours)
Oxygenation indices
This study aims to investigate the effects of Trendelenburg position and pneumoperitoneum on SpO2/FiO2 in ASA I-III patients undergoing robot-assisted laparoscopic surgery.
Time frame: during the surgery and immediately after the surgery (approximately 3 hours to 6 hours)
Oxygenation indices
This study aims to investigate the effects of Trendelenburg position and pneumoperitoneum on OI (oxygenation index) in ASA I-III patients undergoing robot-assisted laparoscopic surgery.
Time frame: during the surgery and immediately after the surgery (approximately 3 hours to 6 hours)
Oxygenation indices
This study aims to investigate the effects of Trendelenburg position and pneumoperitoneum on OSI (oxygenation saturation index) in ASA I-III patients undergoing robot-assisted laparoscopic surgery.
Time frame: during the surgery and immediately after the surgery (approximately 3 hours to 6 hours)
Mechanical ventilator parameters
Change in PEEP (cmH2O) with Trendelenburg position and pneumoperitoneum
Time frame: during the surgery and immediately after the surgery (approximately 3 hours to 6 hours)
Mechanical ventilator parameters
Change in compliance (mL/cmH2O) with Trendelenburg position and pneumoperitoneum
Time frame: during the surgery and immediately after the surgery (approximately 3 hours to 6 hours)
Mechanical ventilator parameters
Change in peak pressure (cmH2O) with Trendelenburg position and pneumoperitoneum
Time frame: during the surgery and immediately after the surgery (approximately 3 hours to 6 hours)
Arterial blood gas parameters
Change in the pH with Trendelenburg position and pneumoperitoneum
Time frame: during the surgery and immediately after the surgery (approximately 3 hours to 6 hours)
Arterial blood gas parameters
Change in the base excess(mmol/lt) with Trendelenburg position and pneumoperitoneum
Time frame: during the surgery and immediately after the surgery (approximately 3 hours to 6 hours)
Arterial blood gas parameters
Change in the partial oxgyen(mmHg) with Trendelenburg position and pneumoperitoneum
Time frame: during the surgery and immediately after the surgery (approximately 3 hours to 6 hours)
Arterial blood gas parameters
Change in the partial carbon dioxide(mmHg) with Trendelenburg position and pneumoperitoneum
Time frame: during the surgery and immediately after the surgery (approximately 3 hours to 6 hours)
Arterial blood gas parameters
Change in the lactate(mmol/lt) with Trendelenburg position and pneumoperitoneum
Time frame: during the surgery and immediately after the surgery (approximately 3 hours to 6 hours)
Hemodynamic parameters
Change in the heart rate with Trendelenburg position and pneumoperitoneum
Time frame: during the surgery and immediately after the surgery (approximately 3 hours to 6 hours)
Hemodynamic parameters
Change in the mean arterial blood pressure with Trendelenburg position and pneumoperitoneum
Time frame: during the surgery and immediately after the surgery (approximately 3 hours to 6 hours)