The study is being conducted to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple doses of HRS9531tablets in healthy subjects.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
72
The Second Hospital Of Anhui medical University
Hefei, Anhui, China
SAD Stage: Number of Adverse Events
Time frame: 36 days
MAD Stage: Number of Adverse Events
Time frame: 63 days
Plasma Concentration-Time to Peak (Tmax) of HRS9531
Tmax of a single dose of HRS9531 tablets
Time frame: 36 days
Area Under the Plasma Concentration-Time Curve (AUC) of HRS9531
AUC of a single dose of HRS9531 tablets
Time frame: 36 days
Immunogenicity qualitative
anti-HRS9531 antibody
Time frame: 36 days
Plasma Concentration-Time to Peak (Tmax) of HRS9531
Tmax of multiple dose of HRS9531 tablets
Time frame: 63 days
Area Under the Plasma Concentration-Time Curve (AUC) of HRS9531
AUC of multiple dose of HRS9531 tablets
Time frame: 63 days
Glucose
fasting plasma glucose
Time frame: 35 days
Immunogenicity qualitative
anti-HRS9531 antibody
Time frame: 63 days
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Multiple dose of placebo in healthy adults