The Efficacy and Safety of Platelet-rich Fibrin and Platelet Rich Plasma in Female Pattern Hair Loss Patients

Siriraj Hospital10 enrolled

Overview

The goal of this clinical trial is to compare between platelet-rich fibrin and platelet-rich plasma in female pattern hair loss . The main question\[s\] it aims to answer are: * efficacy between platelet-rich fibrin and platelet-rich plasma * safety between platelet-rich fibrin and platelet-rich plasma Participants will be divided into 2 side of treatment with composed of 1. Platelet rich plasma 2. Platelet rich fibrin

Subject was treated both platelet-rich fibrin and platelet-rich plasma for 3 times which 1 month interval then will be followed up at 4 months and 6 months after last treatment

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Female Pattern Hair Loss Platelet-Rich Plasma Platelet-rich Fibrin

Interventions

Eligibility

Sex: FEMALEMin age: 20 YearsMax age: 55 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Age 20-55 years * Female * Subject who was diagnosed with Female pattern hair loss in Ludwig Classification 2 (part width 2-4 centimeters) by Dermatologist Exclusion Criteria: * Pregnancy or Lactation subjects * Subject with history of platelet dysfunction, low platelet, anemia, cirrhosis, cancer, or immunocompromised host * Subject who are active smoking and alcoholism * Subject who has dermatitis, scar or infection at intervention area * Subject who has history of allergy to anesthesia drug * Subject who taking NSAIDs, Hormonal drug, anticoagulants drug * Subject who has psychiatric condition diagnosed by psychiatrist * Subject who are not allowed to take a photo

Locations (2)

Faculty of Medicine Siriraj Hospital, Mahidol University

Bangkok Noi, Bangkok, Thailand

RECRUITING

Medicine Siriraj Hospital, Mahidol University

Bangkok Noi, Bangkok, Thailand

RECRUITING

Outcomes

Primary Outcomes

Trichoscan

Average counts and density of hair per 1.5mm\^2

Time frame: baseline(week0), 4 months after last treatment(week20), 6 months after last treatment(week28)

Secondary Outcomes

The 7-point of doctor subjective global assessment

Evaluation of improvement through picture by doctor

Time frame: baseline(week0),1 month after first treatment(week4), 1 months after second treatment(week8), 4 months after last treatment(week20), 6 months after last treatment(week28)

The 7-point of patient subjective global assessment

Evaluation of improvement through picture by patient

Time frame: baseline(week0),1 month after first treatment(week4), 1 months after second treatment(week8), 4 months after last treatment(week20), 6 months after last treatment(week28)

Visual analog scale

pain during intervention

Time frame: baseline(week0), 1 month after first treatment(week4), 1 months after second treatment(week8)

Central Contacts

Rattapon Thuangtong, Asst. Prof.

CONTACT

+66815533305 rattaponthuangtong@yahoo.com

Noldtawat Viriyaskultorn, MD

CONTACT

+66819228736 noldtawat.vir@gmail.com