Treatment of Tempromandibular Joint Anterior Disc Displacement With Different Materials

Mansoura University60 enrolled

Overview

comparing the clinical efficacy of intra-articular injection of platelet lysate (PL), versus Hyaluronic Acid after arthrocentesis in the management of patients with anterior disc displacement with reduction.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

Conditions

TMJ Disc Disorder

Interventions

intra-articular injection with Platelet lysate (PL).PROCEDURE

2 ml of Platelet lysate will be deposited into the superior joint space (SJS) in the affected joint at the entry point slowly

intra-articular injection with Hyaluronic Acid.PROCEDURE

2 ml of Hyaluronic Acid will be deposited into the superior joint space (SJS) in the affected joint at the entry point slowly.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 60 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Patients that will be diagnosed with anterior disc displacement with reduction (ADDWR) both clinically and through magnetic resonance imaging scan (MRI). * Patients who will not respond to a previous conservative therapy. * Patients with pain in temporomandibular joints. * Patients with normal or limitation in mouth opening. * Patients with clicking sound. Exclusion Criteria: * Patients with previous invasive TMJ surgical procedures. * Patients with inflammatory or connective tissue diseases. * Patients with neurologic disorders. * Patients with history of bony or fibrous adhesion. * Patients having gross mechanical restrictions and condylar fractures. * Patients with psychological problems. * Patients receiving anti-coagulation treatment, non-steroidal anti-inflammatory drugs within 48 hours pre-operatively, corticosteroid injection at the treatment site within one month or systemic use of corticosteroids within 2 weeks.

Locations (1)

Heba Elsheikh

Mansoura, Egypt, Egypt

Outcomes

Primary Outcomes

Maximum inter-incisal opening

Maximum inter-incisal opening will be measured by Vernier caliper and this will be recorded by photographs.

Time frame: 6 months

Data from ClinicalTrials.gov

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