Influence of Variable Inflow Volume, Dwell Duration and Glucose Concentration on Ultrafiltration Volume in APD Patients

Inclusion Criteria: * Informed consent signed and dated by study patient and investigator/ authorized physician * Patients between 18-65 of age * Chronic kidney disease (CKD) patients being treated with nocturnal APD for at least 3 months * Ability to understand the nature and requirements of the study * Total Kt/V ≥ 1.7 (counting from recruitment of the patient the measurement should not be older than 3 months) * APD patients using sleep•safe PD-cycler or sleep•safe harmony PD-cycler with an IPP ≤ 18 cm H2O for the fill volume of 120% Exclusion Criteria: * Any condition which could interfere with the patient's ability to comply with the study * Patients who have any condition prohibiting the use of BCM, like patients with major amputations (e.g. lower leg) * Patients who have been subject to peritonitis/ exit site infection during the last 4 weeks * Women of childbearing age without effective means of contraception, pregnancy (pregnancy test will be conducted at start and end of study) or lactation period * Life expectancy \< 3 months * Patients suffering from uncontrolled/ not well adjustable diabetes * Recent history of drain related problems, catheter malfunction, or frequent alarms during treatment * Patients with uncontrolled hypertension and/ or previous history of vascular instability during PD * Patients treated with intermittent APD * Participation in an interventional clinical study during the preceding 30 days * Previous participation in the same study * APD patients having dwell exchanges throughout the day ("day dwell")