Total knee arthroplasty is a safe procedure with excellent outcome. In recent years, simultaneous bilateral total knee arthroplasty has become more popular. In views of enhanced recovery after surgery, intraarticular cocktail injection for pain control has been developed. However, the safety accumulation dose for simultaneous bilateral knee injection is still an issue. Recently, adding magnesium sulfate to intraarticular cocktail injection in unilateral total knee arthroplasty has been proved effective for prolong pain control. We tempt to conduct a double blinded study to evaluate that whether adding magnesium sulfate intraarticular cocktail injection to one of the knees in simultaneous bilateral total knee arthroplasty patient could effectively decrease pain score with less analgesia dose or not.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
80
adding 300mg magnesium sulfate into cocktail injection
VAS score
Time frame: day 0, day 1, day 2, day 3, day 7
muscle power
Time frame: day 0, day 1, day 2, day 3
Straight leg raised test
Time frame: day 0, day 1, day 2, day 3
active range of motion
Time frame: day 0, day 1, day 2, day 3
Magnesium level in blood
Time frame: day 0, day 1
Calcium level in blood
Time frame: day 0, day 1
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