Fragility Re-fractures Prediction Score

I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio800 enrolled

Overview

Fragility fractures increase among elderly patients worldwide, representing a global burden in terms of disability and care expenditure. Osteoporosis is asymptomatic up to the moment in which a first fracture occurs, reason why it is often underdiagnosed. Even after that, further fractures do occurr, as osteoporosis is often untreated. Several programs have been introduced worldwide to prevent secondary fractures among the population at risk (e.g., International Osteoporosis Foundation's Capture the Fracture), and several risk factors are being investigated to generate a predictive score. However, accurate validation is needed to make these scores reliable. In this retrospective observational study, we aim to validate a predictive score trained on a population of elderly patients with a cohort of patients who underwent hip fracture surgery in a high-volume orthopedic center in the Region of Lombardy.

Study Type

OBSERVATIONAL

Enrollment

800

Conditions

Osteoporosis Risk

Interventions

Hip arthroplastyOTHER

Surgical treatment of the hip after osteoporosis fracture. The focus of the study is the prediction of further fractures (and therefore further surgical procedures) after the first one.

Eligibility

Sex: ALLMin age: 60 Years

Medical Language ↔ Plain English

Inclusion Criteria: * People who underwent total or partial hip replacement (ICD 9 CM 81.51, 81.52) in five years (2013-2017) at the hospital for a compound fracture of the hip (ICD 9 CM 820, 820.01-820.09). Exclusion Criteria: * People undergoing the same intervention for other reasons (e.g. pathological fracture, ICD 9 CM 733.14). ICD 9 CM stands for International Classification of Disease, 9th Revision, Clinical Modification.

Outcomes

Primary Outcomes

Age, sex, disease name and body mass index (weight in kg and height in m will be combined to report BMI in kg/m^2)

Patient characteristics and comorbidities associated with a fragility fracture of the hip

Time frame: Baseline: the outcomes are assessed before surgery