Transverse maxillary deficiency is a common orthodontic issue, affecting around 10% of adults. Late adolescents and adults often require more force to expand the midpalatal suture due to its increased interdigitation. This study aims to assess the effectiveness of MARPE in this demographic and determine the best activation protocol for non-surgical maxillary expansion using mini-screw-supported appliances. Additionally, the study will evaluate the effectiveness of MARPE on nasal permeability and airway volume.
The study design comprised a three-arm, parallel-group randomized controlled trial (RCT) conducted at the Orthodontics clinic of Brussels University Hospital. Patients were randomly allocated into one of three groups: 1. Continuous rapid activation protocol: Patients received one activation of 0.17 mm per day until reaching the clinical goal. 2. Continuous slow activation protocol: Patients underwent two activations (0.33 mm) per day for the first 7 days, followed by one turn forward every third day (0.17 mm / 3 days). 3. Force-controlled polycyclic protocol: Patients underwent two activations (0.33 mm) per day for the first 7 days. Then, the hex nut was turned 6 sides backward, followed by 6 sides forward after 15 minutes. Additionally, the device was activated by 0.17 mm every third day. Intervention: All patients underwent maxillary expansion with MARPE. Four orthodontic mini-screws were inserted under local anesthesia using a surgical guide and motor. Surgical incision was not required, and predrilling was performed if necessary. The MARPE remained in place for 12 months after expansion to allow bone remodeling in the midpalatal suture. Fixed straight-wire treatment commenced 2 months after expansion termination. Patients underwent retention check-ups at 6 and 12 months post-expansion, and expansion screws and mini-screws were removed after 12 months or before orthognathic surgery, if applicable. The specific aims of the study were to evaluate the success rate of nonsurgical maxillary expansion, compare the efficacy of the three activation protocols, assess and compare complications, analyze the correlation between success rate and Midpalatal Suture Maturation Stage (MPS), age, and sex, and measure nasal permeability variation using anterior rhinomanometry.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
The intervention involved the placement of orthodontic mini-screws in the patient's palate, varying in diameter from 2 to 2.3 mm and in length from 11 to 15 mm. After mini-screw insertion, another intraoral scan was taken for the fabrication of the appliance. Approximately three weeks later, the expander was placed in the patient's palate, and maxillary expansion was initiated immediately afterward according to the chosen protocol.
Route de Lennik 900
Anderlecht, Brussels Capital, Belgium
NOT_YET_RECRUITINGservice dentaire et d'orthodontie de l'hopital université de bruxelles (HUB)
Anderlecht, Brussels Capital, Belgium
RECRUITINGMPSM: mid-palatal suture middle molars
the width of the mid-palatal suture measure in millimeters at the level of the first molars
Time frame: up to 6 months
ANS-ANS
the distance in millimeters between the right anterior nasal spine and the left anterior nasal spine after the maxillary expansion
Time frame: up to 6 months
PNS-PNS
distance in millimeters between the right posterior nasal spine and the left posterior nasal spine after the maxillary expansion
Time frame: up to 6 months
UID
distance in millimeters from the most external point of the right frontozygomatic suture to the most external point of the left frontozygomatic suture.
Time frame: up to 6 months
ZMA
width in millimeters between the right and left zygomatic arches at its widest point at the most inferior level of the orbits.
Time frame: up to 6 months
LID:
distance in millimeters from the most external point of the right zygomaticomaxillary suture to the most external point of the left zygomaticomaxillary suture
Time frame: up to 6 months
NCW: nasal cavity width
Transverse distance in millimeters between the left and right most lateral point of the nasal cavity
Time frame: up to 6 months
MSW: midpalatal suture width
Transverse distance in millimeters between the medial limits of the left and right palatal process at the palatal floor
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
TREATMENT
Masking
SINGLE
Enrollment
60
Time frame: up to 6 months
IMW: intermolar width
Transverse distance in millimeters between the left and right maxillary M1 mesiocentral fossae
Time frame: up to 6 months
IPW: interpremolar width
Transverse distance in millimeters between the left and right maxillary P1 mesial fossae
Time frame: up to 6 months
ICW: intercanine width
Transverse distance in millimeters between the left and right maxillary canine buccal cusp tips
Time frame: up to 6 months
PAW: palatal alveolar width
Transverse distance between in millimeters the left and right most cervical medial limits of the palatal alveolar process
Time frame: up to 6 months
TI : tooth inclination
2D inner angle (in degrees) between the palatal plane and the left and right line running through the palatal apex and the mesiobuccal fossa or the mesial fossa
Time frame: up to 6 months
RT resistance total
Total bilateral nasal resistance in Pa.s.cm³
Time frame: up to 6 months
NCV: nasal cavity volume
nasal cavity volume in mm3
Time frame: up to 6 months
RMSV : right maxillary sinus volume
Right maxillary sinus volume in mm3
Time frame: up to 6 months
LMSV : left maxillary sinus volume
left maxillary sinus volume in mm3
Time frame: up to 6 months
NPV nasopharynx volume
nasopharynx volume in mm3
Time frame: up to 6 months
OPV oropharynx volume
OPV oropharynx volume in mm3
Time frame: up to 6 months
OMCSA: oropharynx minimum cross-sectional area
oropharynx minimum cross-sectional area in mm2
Time frame: up to 6 months
AV: Accumulated volume
which represents the total volume in mm3, is calculated using the sum of the NCV, RMSV, LMSV, NPV, and OPV
Time frame: up to 6 months