Efficacy of Platelet-rich Plasma Injection Compare With Corticosteroid in Pes Anserinus Pain Syndrome

Overview

The goal of this research is to study the efficacy of treatment between PRP injection and corticosteroid injection in patients with pes anserinus bursitis. The research question is whether PRP can reduce pain more effectively than corticosteroids. The study is divided into two groups: one group receiving PRP injections and the second group receiving corticosteroid injections. Treatment outcomes will be monitored at four time points: baseline, 4 weeks, 12 weeks, and 24 weeks. The outcomes will be measured using the VAS and WOMAC scores.

Randomization of patient with pes anserinus bursitis at opd od ramathibodi hospital. Objective : to study the efficacy of treatment between PRP injection and corticosteroid injection in patients with pes anserinus bursitis Medhods : A randomized controlled trial , Single blinded Participants : Patients with pes anserinus bursitis Randomization : Randomization will be performed using the software STATA 16.0 (StataCorp, College Station, Texas, USA). A various blocked randomization method Interventions and control : * Experimental groups : PRP injection 4 ml * Control groups : Steroid injection , Triamcinolone acetonide(40mg/ml) 1 ml + 1%Lidocaine without adrenaline 3 ml = 4ml By Orthopedic surgeon with ultrasound guide. Allocation and concealment : A central randomization service will prepare sealed envelopes containing the assigned treatment for each patient. The envelopes will be kept in secure location until Break the concealment at outpatient orthopedics department , Ramathibodi hospital Blinding : Randomized controlled trial study, Single blinded The assessor who will be follow up the patients, will be blinded to the group assignments. Outcome measures: Visual Analogue Scale (VAS) , Womac scores Follow up: at 4 weeks, 12 weeks, and 24 weeks after injection. Statistic analysis: STATA 16.0, StataCorp, College Station, Texas, USA Analysis Demographic data : mean, SD Mean difference in patient-relevant outcomes : Independent T- test