Determination of Risk Factors of Shoulder Pathologies in Parkinson Disease

N/ANot Yet RecruitingNCT06456840

Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey160 enrolled

Overview

Parkinson's disease was first described in history in 1817 by James Parkinson in his monograph "An essay on swinging palsy", and today it is the 2nd most common neurodegenerative disease after Alzheimer's, affecting approximately 6.1 million people. Its main histopathological feature is the decrease in dopaminergic secretion in the basal ganglia and there are three cardinal findings: Bradykinesia, Tremor, Rigidity. Although joint and skeletal deformities are seen in approximately 70% of Parkinson's patients, they are not adequately evaluated and cause significant functional disability and chronic pain, independent of motor symptoms.Musculoskeletal pathologies seen in Parkinson's patients can be classified as: musculoskeletal pain, articular problems, postural problems and bone mineralization defects. The shoulder girdle is a joint with complex and delicate function, consisting of four joints (glenohumeral, sternoclavicular, acromioclavicular and scapulothoracic), supporting muscles and periarticular ligaments, which seriously affects the patient's quality of daily life and function. Although magnetic resonance imaging (MRI) is the best imaging tool in the diagnosis of musculoskeletal system pathologies, it is quite sensitive to artifact-forming motion. Ultrasound (US) imaging is widely used in the evaluation of rotator cuff muscles, biceps muscle and glenohumeral joint pathologies and has many advantages over MRI, such as providing fast, cheap and dynamic imaging. Although many studies have proven that shoulder girdle musculoskeletal pathologies such as bicipital tendinitis, m.supraspinatus tendinosis, subacromial/subdeltoid bursitis, subacromial impingement syndrome, and adhesive capsulitis are seen more frequently in Parkinson's patients by ultrasonographic imaging, these shoulder girdle pathologies seen in Parkinson's patients are more common. The risk factors for pathologies have not been defined. In this study, we aimed to determine the ultrasonographic findings and risk factors of shoulder pathologies in Parkinson's patients and to investigate the effects of shoulder pathologies on quality of daily life, physical activity, falls and balance.

Study Type

OBSERVATIONAL

Enrollment

160

Conditions

Parkinson Disease

Interventions

ULTRASOUNDDIAGNOSTIC_TEST

Measurements will be made in musculoskeletal system ultrasonography by an international Medicine and Rehabilitation assistant physician using images obtained with the Sonosite M-Turbo device using the ImageJ program. During the measurements, the patient and the patient will be face to face and the device will be placed postero-laterally. Five standard window spacings will be used for the shoulder attachment. These are: anterior transverse, anterior longitudinal, lateral longitudinal, lateral transverse, posterior transverse.

Eligibility

Sex: ALLMin age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: Group1 * Being diagnosed with Parkinson's according to the Movement Disorders Society diagnostic criteria * Being over 50 years old * Being in the Hoehn \& Yahr stage I-IV range * Identification of pain in at least one shoulder (VAS\>3) * Agreeing to participate in the study * Being literate Group2 * Being diagnosed with Parkinson's according to the Movement Disorders Society diagnostic criteria * Being over 50 years old * Being in the Hoehn \& Yahr stage I-IV range * No pain in both shoulders (VAS: 0) * Agreeing to participate in the study * Being literate Group 3 * Describe pain \>3 on the visual pain scale in any shoulder * Being over 50 years old * Becoming literate * Agreeing to participate in the study Group 4 1. Not defining pain with a score of 0 on the visual pain scale in both shoulders 2. Being over 50 years old 3. Being literate 4. Agreeing to participate in the study Exclusion Criteria: * Scoring less than 24 points in the Mini Mental Test * Having had a myocardial infarction * Having had a cerebrovascular accident * Having a rheumatological disease * Known endocrine disease (Diabetes Mellitus, Hypo/hyperthyroidism) * Cervical disc herniation defining radiculopathy * Active trigger point palpated in the shoulder girdle muscles * Having had any shoulder surgery * Concomitant history of active systemic inflammatory disease, active infection and active malignancy * Physical Therapy modalities have been applied in the last 6 months * Having had an interventional procedure performed on the shoulder area within the last 6 months * Using medications that may cause tendinopathy (Fluoroquinolines)

Outcomes

Primary Outcomes

USG FINDINGS

Measurements will be made by a Physical Medicine and Rehabilitation assistant physician experienced in musculoskeletal system ultrasonography, using the images obtained with the Sonosite M-Turbo device using the ImageJ program. During the measurements, the device will be positioned on the postero-lateral side of the patient while the patient and the practitioner are face to face. Five standard viewing windows will be used for the shoulder joint. These are: anterior transverse, anterior longitudinal, lateral longitudinal, lateral transverse, posterior transverse.

Time frame: ONE MONTH