To Evaluate the Efficacy and Safety of Tegileridine and Oliceridine Injections in the Treatment of Postoperative Pain

Inclusion Criteria: 1. Accept elective laparoscopic combined thoracic surgery under general anesthesia, surgery time ≥ 1 h; 2. 18 years old ≤ age ≤70 years old, regardless of gender; 3. 18 kg/m2≤BMI≤30 kg/m2; 4. American Society of Anesthesiologists (ASA) grade ⅰ-ⅲ; 5. Within 4 hours after the end of surgery, NRS≥4 in the resting state at any time; 6. Before starting trial-related activities, participants should voluntarily sign the informed consent form, fully understand the purpose and significance of this trial, and voluntarily abide by the trial procedures. Exclusion Criteria: 1. Patients with a previous history of difficult airway (obstructive sleep apnea syndrome), severe respiratory depression such as oxygen saturation \< 90%, or a history of acute or severe bronchial asthma; 2. Patients with a history of severe cardiovascular and cerebrovascular diseases (such as myocardial infarction or unstable angina pectoris, or severe arrhythmia such as atrioventricular block of degree Ⅱ or above, or ischemic stroke in NYHA class Ⅱ or above); 3. Known or suspected gastric bowel obstruction, including paralytic ileus patients; 4. Patients with allergy to opioids or any component of the trial drug; 5. Subjects with previous psychiatric disorders (such as schizophrenia, depression, etc.) and cognitive impairment; 6. With late-stage malignant tumors or with extensive metastasis of malignant tumor patients; 7. Subjects with other somatic pain that may affect postoperative pain assessment; 8. A history of drug, drug, and/or alcohol abuse within 1 year before randomization; 9. Pregnant or lactating female subjects; 10. Subjects with any other factor considered by the investigator to be ineligible for participation in the trial.