High Flow Nasal Cannula is Appropriate Alternative for Stabilization of Very Premature Infants: a Prospective Observational Study

Charles University, Czech Republic65 enrolled

Overview

A prospective observational study evaluates the safety and efficacy of using High-Flow Nasal Cannula to stabilize very preterm infants immediately after birth. Following placental transfusion, high flow nasal cannula at 8 l/min is administered along with intermittent tactile stimulation. Criteria for switching to other interventions like continuous positive airway pressure or positive pressure ventilation are set for cases of persistent bradycardia or low SpO2.

Study Type

INTERVENTIONAL

Allocation

Purpose

OTHER

Masking

NONE

Enrollment

Conditions

Premature; Infant

Interventions

High-Flow Nasal CannulaDEVICE

The intervention involves administering High-Flow Nasal Cannula therapy to very preterm infants immediately after birth.

Eligibility

Sex: ALLMin age: 0 MinutesMax age: 2 Minutes

Medical Language ↔ Plain English

Inclusion Criteria: * Preterm infants born between 28+0 and 31+6 gestational weeks were enrolled in the study after obtaining parental informed consent. Exclusion Criteria: * Infants with congenital malformations, previable rupture of membranes, and acute intrauterine hypoxia.

Locations (1)

Charles University in Prague

Prague, Czech, Czechia

Outcomes

Primary Outcomes

HFNC slabilization

Number of infants who were stabilized after birth on high flow nasal cannula exclusively without any other use of artificial external pressures.

Time frame: 10 minutes after delivery

Data from ClinicalTrials.gov

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