Perioperative Database of Chinese Elderly Patients for Postoperative Acute Kidney Injury

Chinese PLA General Hospital57,089 enrolled

Overview

To develop and externally validate a risk prediction model for postoperative acute kidney injury (PO-AKI) in elderly patients undergoing major noncardiac surgery, addressing the current gap in predictive tools for this vulnerable population. The endpoint was the occurrence of PO-AKI within seven days following surgery. Diagnoses were based on the Kidney Disease: Improving Global Outcomes (KDIGO) criterion. Potential PO-AKI-related perioperative data were retrieved and extracted from electronic medical record for model derivation and validation. Clinicians may consider implementing this externally validated risk prediction model to stratify elderly patients' PO-AKI risks in the early postoperative phases of noncardiac surgery in elderly patients.

Study Type

OBSERVATIONAL

Enrollment

57,089

Conditions

Postoperative Acute Kidney Injury

Interventions

No interventionOTHER

no intervention

Eligibility

Medical Language ↔ Plain English

Inclusion Criteria: * elderly patients (aged ≥ 65 years) undergoing non-cardiac surgeries Exclusion Criteria: * (1) Patients who underwent endoscopic or transplant procedures; * (2) Patients who underwent surgeries lasting longer than 10 hours; * (3) Patients who had severe preoperative kidney dysfunction, defined as preoperative sCr levels ≥ 353.6 μmol/L, or a baseline estimated Glomerular Filtration Rate (eGFR) \< 15 ml/min per 1.73 m2; * (4) Patients without sCr values at baseline or during follow-up to detect PO-AKI occurrences.

Outcomes

Primary Outcomes

Number of participants with postoperative acute kidney injury

Postoperative acute kidney injury

Time frame: within seven days following surgery