This study aims to understand the ideal formulation to utilize in saphenous nerve and popliteal nerve blocks for foot and ankle procedures. It will examine the use of liposomal bupivacaine alone or liposomal bupivacaine with dexamethasone prior to foot and ankle procedures in peripheral nerve blocks. We will compare liposomal bupivacaine (Exparel) and liposomal bupivacaine (Exparel) combined with dexamethasone to determine if the addition of dexamethasone significantly decreases postoperative narcotic use and prolongs analgesic effects when administered in a popliteal and saphenous block prior to foot and ankle orthopedic procedures.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
126
20 mL Liposomal bupivacaine (Exparel, 266 mg) will be administered in the popliteal and saphenous block
10 mL of 0.75% bupivacaine will be administered in popliteal and saphenous block
1 mL of 10 mg Dexamethasone will be administered in the popliteal and saphenous block
Rothman Orthopaedic Institute
Philadelphia, Pennsylvania, United States
Amount of pain medication used after surgery
Collected as tablets taken since all participants will be prescribed oxycodone
Time frame: 14 days
Pain level after surgery
Participants will be asked daily what their pain levels are using the Visual Analog (VAS) pain scale
Time frame: 14 days
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