The Obstructive Sleep Apnea hypopnea Syndrome (OSAS), whose prevalence is 4% of the French population, can lead to serious health consequences (risk of road accidents, onset of cardiovascular disease, etc.). OSAS corresponds to a certain number of interruptions (apneas) or reductions (hypopneas) of ventilation during sleep. The weakening of the tone of the inspiratory and oropharyngeal muscles is one of the main causes of upper airways obstruction during the inspiratory phase.
For patients with moderate OSAS, with few or no symptoms, without associated cardiovascular comorbidities, there is no recommended treatment. Rehabilitate the inspiratory and oropharyngeal muscles through muscle strengthening seems to be an alternative to this problem. Therefore, this study proposes a complete rehabilitation care evaluating the effectiveness of the strengthening of inspiratory and oropharyngeal muscles in subject with moderate OSAS.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
38
Patients will conduct the training at home, 5 days a week for 3 months. They will perform 2 sets of 30 inspirations against resistance (POWERbreathe® K5 , Powerbreathe International Limited, UK), equal to 70% Maximum Inspiratory Pressure (MIP). Patients will be guided for oropharyngeal exercises. The sessions will be supervised by the investigator every 3 weeks. During sessions with the investigator, sessions recorded in the device will be downloaded to verify compliance. A MIP measurement will be performed to adjust the resistance of the device.
CHU de Grenoble
Grenoble, France
NOT_YET_RECRUITINGCentre Hospitalier Universitaire
Saint-Etienne, France
RECRUITINGApnea-Hypopnea Index (AHI)
AHI is measured by polygraphy or polysomnography. It is not a score
Time frame: At 3 months
Maximum inspiratory pressure measurement (cmH2O)
Measured by POWERbreathe® K5
Time frame: At 3 and 9 Months
Neck circumference (cm)
The neck circumference is measured by Magnetic Resonance Imagery (RMI)
Time frame: At 3 months
Epworth sleepiness score
Sleep quality assessment using the Epworth sleepiness score. From 0 to 24. If score up to 10 then the patient has signs of excessive daytime sleepiness
Time frame: At 3 and 9 Months
Pittsburgh Sleep quality index
Sleep quality assessment using the Pittsburgh Sleep quality index. From 0 to 21. Score 0 = very good sleep quality. Score 21 = very poor sleep quality
Time frame: At 3 and 9 Months
Quality of life scale : Short Form 12 (SF12)
Quality of life assessment using the scale SF12 From 43 to 118 the higher the score, the better the quality of life
Time frame: At 3 and 9 Months
PICOT fatigue scale
Fatigue assessment using the PICOT scale From 0 to 32 If score up to 22 then the patient has signs of excessive sleepiness
Time frame: At 3 and 9 Months
AHI (Apnea-Hypopnea Index)
AHI is measured by polygraphy or polysomnography It is not a score
Time frame: At 9 months
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