Interactions Between Environmental Exposures and Gut Microbiota in Early Life

Peking University People's Hospital756 enrolled

Overview

Recruit the mothers and their infants who bron in Peking University People's Hospital from 2023 to 2026, to evaluate the interaction between environmental exposure and gut microbiota.

Study Type

OBSERVATIONAL

Enrollment

756

Conditions

Infant Development

Interventions

delivery modeOTHER

Based on delivery mode, we will divide them into two groups, including Cesarean section and Natural delivery.

Eligibility

Sex: ALLMin age: 1 DayMax age: 24 MonthsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. Pregnant woman * aged 20-40 years old * natural conception * single pregnancy * gestational age ≥36 weeks 2. Newborn * normal Apgar score * no serious congenital diseases Exclusion Criteria: \-

Locations (1)

The Peking University People's Hospital

Beijing, China

RECRUITING

Outcomes

Primary Outcomes

Arsenic levels and Gut microbiota

Arsenic levels in biological samples; gut microbiota and metabolites in stools.

Time frame: Pregnancy (12, 24, 36 weeks) and infants (born, 1 week, and 1, 3, 6, 12, 24 months)

Central Contacts

Xue Xu, Dr.

CONTACT

010-88324385 xuxue19877182@sina.com

Data from ClinicalTrials.gov

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