The prevalence of chronic diseases is increasing globally. In recent years, intermittent fasting has emerged as an effective dietary pattern against some of the most common chronic diseases in the elderly, alongside the Mediterranean diet. The objective was to determine whether a 12-hour daily intermittent fasting regimen combined with a Mediterranean diet can improve analytical and anthropometric values in the elderly. A total of 17 individuals of both sexes, over 60 years old, autonomous, and with preserved cognitive capacity participated. They were randomly divided into two groups: 8 people in the intervention group performed intermittent fasting along with a Mediterranean diet, and 9 in the control group adopted only a Mediterranean diet. The intervention lasted 3 months, with measurements taken at the beginning and end of the intervention.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
17
8 participants who practiced a 12/12 TRF (12 hours of fasting, from approximately 20:30 to 8:30 the following day).
A control group consisting of 9 participants who followed a standard Mediterranean diet.
University of Zaragoza
Zaragoza, Spain
Biochemical values (mg/dL)
Basal glucose, High-Density Lipoprotein, Low-Density Lipoprotein, total cholesterol, triglycerides, serum transferrin, urea, uric acid, creatinine.
Time frame: 12 weeks
Blood Pressure (mmHg)
Blood pressure (Systolic blood pressure, diastolic blood pressure)
Time frame: 12 weeks
Anthropometric values (kg)
Weight
Time frame: 12 weeks
Anthropometric values (cm)
Weight, waist circumference, hip circumference.
Time frame: 12 weeks
Anthropometric values (kg/m^2)
Body mass index.
Time frame: 12 weeks
Anthropometric index (numerical rating scale)
Atherogenic index of plasma, waist/hip ratio.
Time frame: 12 weeks
Biochemical values (IU/L)
Alkaline phosphatase, aspartate aminotransferase, alanine aminotransferase, gamma-glutamyltransferase
Time frame: 12 weeks
Biochemical values (mg/L)
C-Reactive Protein
Time frame: 12 weeks
Biochemical values (µg/L)
Serum ferritin
Time frame: 12 weeks
Biochemical values (µg/dL)
Iron
Time frame: 12 weeks
Biochemical values (g/dL)
Albumin
Time frame: 12 weeks
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