DAO DEFICIENCY SCREENING AMONG PATIENTS WITH INSOMNIA SYMPTOMS

AB Biotek200 enrolled

Overview

Insomnia is prevalent in the global population. Diamino oxidase (DAO) is an enzyme that degrades histamine. When there is not enough DAO enzyme activity in the body, histamine accumulates and it can lead to symptoms in the nervous system, among others. In this study we wanted to study the prevalence of DAO deficiency in pacients with insomnia symptoms.

Study Type

OBSERVATIONAL

Enrollment

200

Conditions

Insomnia Insomnia Disorder

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Older than 18 years old * With one or more symptoms of insomnia * Explicit acceptance to participate to the study through informed consent Exclusion Criteria: * Insomnia symptoms that could be justified by the existance of another sleep pathology (e.g., narcolepsy)

Locations (1)

AdSalutem Sleep Institute

Barcelona, Barcelona, Spain

Outcomes

Primary Outcomes

number of patients with insomnia symptoms and DAO deficiency

number (absolute and percentage) of patients with insomnia symptoms and DAO deficiency

Time frame: at the time of enrollment

Data from ClinicalTrials.gov

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