The main objective of this nutritional intervention is to assess the efficacy of polyphenol-rich capsules on reducing metabolic syndrome traits, mainly cholesterol levels. For this purpose, a double blind, placebo controlled study of 12 weeks will be carried out. The target population is women and men with overweight or obesity. Researchers will compare the experimental capsules with placebo capsules, but will be blinded during the intervention and results analyses. Only after analysing the parameters, the groups will be revealed.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Enrollment
100
Three capsules in fasting conditions 15 minutes prior breakfast
Three capsules in fasting conditions 15 minutes before breakfast
Centro de Investigacion en Nutricion. Universidad de Navarra
Pamplona, Navarre, Spain
Total cholesterol
Serum concentration of Total Cholesterol
Time frame: Baseline
Total cholesterol
Serum concentration of Total Cholesterol
Time frame: 12 weeks
HDL cholesterol
Serum concentration of HDL cholesterol
Time frame: Baseline
HDL cholesterol
Serum concentration of HDL cholesterol
Time frame: 12 weeks
LDL cholesterol
Serum Calculated LDL Cholesterol levels
Time frame: Baseline
LDL cholesterol
Serum Calculated LDL Cholesterol levels
Time frame: 12 weeks
Triglycerides
Serum Triglycerides levels
Time frame: Baseline
Triglycerides
Serum Triglycerides levels
Time frame: 12 weeks
Weight
Weight status
Time frame: Baseline
Weight
Weight status
Time frame: 12 weeks
Fat mass
Fat mass in kg, measured by Bioimpedance
Time frame: Baseline
Fat mass
Fat mass in kg, measured by Bioimpedance
Time frame: 12 weeks
Hemoglobin
Hemoglobin measured as mg/dL
Time frame: Baseline
Hemoglobin
Hemoglobin measured as mg/dL
Time frame: 12 weeks
Hematocrit
Hematocrit (%)
Time frame: Baseline
Hematocrit
Hematocrit (%)
Time frame: 12 weeks
Physical Activity
Measured through the IPAQ questionnaire
Time frame: Baseline
Physical Activity
Measured through the IPAQ questionnaire
Time frame: 12 weeks
Blood pressure
Measured in the dominant arm (mmHg)
Time frame: Baseline
Blood pressure
Measured in the dominant arm (mmHg)
Time frame: 12 weeks
Dietary intake
FFQ from the SUN Study
Time frame: Baseline
Dietary intake
FFQ from the SUN Study
Time frame: 12 weeks
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.