The goal of this clinical trial is to learn if dietary supplements containing vitamin and unsaturated fatty acid works to intervene T cell inflammatory factor expression in patients with uveitis and healthy subjects in adults.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
BASIC_SCIENCE
Masking
NONE
Enrollment
7
Vitamin A, 32 microgram per kilograms (of body weight) per day, for three weeks
Monounsaturated fatty acid mixture (mainly Omega-7, Omega-9), 47 milligrams per kilogram (of body weight) per day, for three weeks
Polyunsaturated fatty acid mixture (mainly Omega-3, Omega-6), 6 milligrams per kilogram (of body weight) per day, for three weeks
Tianjin Medical University Eye Hospital
Tianjin, Tianjin Municipality, China
Inflammatory factors-Interleukin-17A (IL-17A)
Flow cytometry analysis of peripheral blood mononuclear cells (PBMCs) to detect the ratio of Interleukin-17A (IL-17A) -producing cells in CD4+ T cells and CD8+ T cells
Time frame: 3 weeks
Inflammatory factors-Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)
Flow cytometry analysis of peripheral blood mononuclear cells (PBMCs) to detect the ratio of Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) -producing cells in CD4+ T cells and CD8+ T cells
Time frame: 3 weeks
Inflammatory factors-Interferon gamma (IFN-γ)
Flow cytometry analysis of peripheral blood mononuclear cells (PBMCs) to detect the ratio of Interferon gamma (IFN-γ) -producing cells in CD4+ T cells and CD8+ T cells
Time frame: 3 weeks
Cytokine levels-Interleukin-17A (IL-17A)
Analysis of cytokine levels in blood. Detect the concention of Interleukin-17A (IL-17A) in plasma
Time frame: 3 weeks
Cytokine levels-Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)
Analysis of cytokine levels in blood. Detect the concention of Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) in plasma
Time frame: 3 weeks
Cytokine levels-Interferon gamma (IFN-γ)
Analysis of cytokine levels in blood. Detect the concention of Interferon gamma (IFN-γ) in plasma
Time frame: 3 weeks
Cytokine levels-Interleukin-2 (IL-2)
Analysis of cytokine levels in blood. Detect the concention of Interleukin-2 (IL-2) in plasma
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Fatty acid mixture (mainly saturated fatty acid, Omega-6, Omega-7, Omega-9), 83 milligrams per kilogram (of body weight) per day, for three weeks
Time frame: 3 weeks
Cytokine levels-Interleukin-10 (IL-10)
Analysis of cytokine levels in blood. Detect the concention of Interleukin-10 (IL-10) in plasma
Time frame: 3 weeks
Cytokine levels-Interleukin-9 (IL-9)
Analysis of cytokine levels in blood. Detect the concention of Interleukin-9 (IL-9) in plasma
Time frame: 3 weeks
Cytokine levels-Interleukin-4 (IL-4)
Analysis of cytokine levels in blood. Detect the concention of Interleukin-4 (IL-4) in plasma
Time frame: 3 weeks
Cytokine levels-Tumor Necrosis Factor alpha (TNF-α)
Analysis of cytokine levels in blood. Detect the concention of Tumor Necrosis Factor alpha (TNF-α) in plasma
Time frame: 3 weeks