Postoperative Anxiety and Depression Among Older Chinese Patients

Chinese PLA General Hospital

Overview

A multicenter, prospective observational study to describe the socioeconomic characteristics and the occurrence of postoperative anxiety and depression in the Chinese old population.

As China's population ages, the proportion of elderly people undergoing surgery increases. Perioperative anxiety and depression, particularly in elderly patients, is common and associated with multiple medical and social adversities. Previous studies have found a 31 percent risk of anxiety and 29 percent risk of depression in older perioperative patients. However, nationally representative epidemiological data for postoperative anxiety and depression, in particular elderly patients undergoing non-cardiac surgery, are unavailable in China. Therefore, providing nationwide epidemiological data on postoperative anxiety and depression in Chinese elderly patients provides a valuable opportunity for policy makers and health care professionals to optimize the management of geriatric mental health in China.

Study Type

OBSERVATIONAL

Conditions

Depression Anxiety Elderly Patients Non-cardiac Surgery

Interventions

no interventionOTHER

no intervention

Eligibility

Sex: ALLMin age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. elderly patients (age ≥ 65 years) 2. undergoing elective surgery with a planned overnight hospital stay following surgery 3. non-cardiac surgery, non-neurosurgical surgery Exclusion Criteria: 1. patients fully refused to participate in the study 2. patients with severe dementia, language disorder, severe hearing or visual impairment, coma, and end-stage status 3. patients whose surgeries were canceled 4. history of previous severe mental illness or long-term use of psychotropic medications 5. patients admitted to ICU immediately after surgery 6. patients who died within 7 days after surgery 7. patients who did not complete the scale assessment

Locations (1)

First Medical center of Chinese PLA General Hospital

Beijing, China

Outcomes

Primary Outcomes

Anxiety

The GAD-7 is a seven-item questionnaire for screening on the presence of generalized anxiety disorder and assessing its severity. Items were scored on a four-point scale with total scores ranging from zero to twenty-one. Scores were defined as: ≥5 mild, ≥10 moderate, and ≥15 severe anxiety. The recommended screening cutoff was ≥10, corresponding with at least a moderate level of anxiety. Higher scores mean more anxiety.

Time frame: within 7 days after surgery

Depression

Primary outcomes were depression Patient Health Questionnaire 9 (PHQ-9).The PHQ-9 is a nine-item questionnaire for screening on the presence of depressive symptoms and monitoring depression severity. Items were scored on a four-point scale with total scores ranging from zero to twenty-seven. Scores were defined as: ≥5 mild, ≥10 moderate, and ≥15 severe level of depression. The recommended screening cutoff was ≥10, corresponding with at least a moderate level of depression. The higher the score, the worse the situation. The total score ranges from 0 to 27, and higher scores indicate more depressive symptoms.

Time frame: within 7 days after surgery

Data from ClinicalTrials.gov

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