Prognostic Significance of Preoperative Nutritional Status on Postoperative Acute Kidney Injury

N/ANot Yet RecruitingNCT06496802

Wanmin Liao1,880 enrolled

Overview

The incidence of postoperative acute kidney injury (AKI) is high in patients undergoing lung resection surgery, especially in the elderly. Early identification of high-risk postoperative AKI patients can help develop prevention and treatment management strategies.

The goal of this retrospective study is to investigate the predictive value of preoperative nutritional status, as measured by three scoring systems - the geriatric nutritional risk index (GNRI), prognostic nutritional index (PNI), and controlling nutritional status (CONUT) score - on postoperative AKI in elderly patients under lung resection surgery.

Study Type

OBSERVATIONAL

Enrollment

1,880

Conditions

Acute Kidney Injury Pneumonectomy

Interventions

no interventionOTHER

no intervention

Eligibility

Sex: ALLMin age: 65 YearsMax age: 100 Years

Medical Language ↔ Plain English

Inclusion Criteria: 1. aged ≥ 65 years 2. lung resection surgery including：pneumonectomy , bilobectomy , lobectomy, segmentectomy, wedge resection/bullectomy. Exclusion Criteria: 1. patients with an American Society of Anesthesiologists (ASA) physical status V. 2. those with end-stage renal disease (i.e. a glomerular filtration rate of 15 mL/min/1.73 m2 or receiving haemodialysis). 3. those did not have sufficient data required for nutritional evaluation or AKI evaluation.

Outcomes

Primary Outcomes

Postoperative acute kidney injury

In accordance with the KDIGO creatinine criteria: a serum creatinine increases of 26.5 mmol/L within 48 hours or 1.5 times baseline within 7 days after surgery.

Time frame: Within 7 days after surgery

Data from ClinicalTrials.gov

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