The trend of myopia in children and its low age is a major social and public health problem in China. More seriously, retinopathy associated with high myopia has become the number one cause of irreversible blinding eye disease in adults in some parts of China. Physiological hyperopia has a protective effect on preventing the onset of myopia, and is one of the strongest predictors of myopia on its own, which is significant in curbing myopia from occurring at a younger age and preventing the development of high myopia before adulthood. However, it is not yet known how the physiological hyperopia changes in childhood, the stage at which the critical inflection point occurs, which key factors lead to the rapid fading of the physiological hyperopia and progression to myopia, and the strength of its effect. In the early stage of the study, the research group established a prospective cohort of preschoolers based on natural population sampling, which included a total of 2109 preschoolers aged 3-6 years from 22 kindergartens in a district in Beijing, and completed a 2-year follow-up, obtaining exploratory results on the changing pattern of physiological hyperopia and key influencing factors in younger children. The group will add new samples to the existing whole cohort sampling cohort and adopt the design scheme of prospective nested case-control study to determine the changing trend of fading trajectory of physiological hyperopia in school-age children, key inflection points and key risk factors, so as to provide new techniques for the prevention and control of childhood myopia.
Study Type
OBSERVATIONAL
Enrollment
1,006
This study was observational with no intervention.
Beijing Tongren Hospital
Beijing, Beijing Municipality, China
RECRUITINGmyopia
Myopia in this study was defined as an equivalent spherical lens degree ( SER ) error (sphere+1/2 cylinder) of at least - 0.5 diopters(D) in either eye.
Time frame: 1 year
Myopia Prevalence
Myopia is defined as a spherical equivalent refractive (SER) (sphere + 1/2 cylinder) of at least -0.5 diopter (D) in either eye.
Time frame: 3 year
The change in ocular axis length
The change in ocular axis length was calculated by subtracting each year's measurement from the previous year's measurement.
Time frame: 3 year
The change in anterior chamber depth
Calculate the change in anterior chamber depth by subtracting each year's measurement from the previous year's measurement.
Time frame: 3 year
The change in corneal curvature
Calculate the change in corneal curvature by subtracting each year's measurement from the previous year's measurement.
Time frame: 3 year
The change in the ratio of axial length to corneal curvature
Calculate the change in the ratio of axial length to corneal curvature by subtracting each year's measurement from the previous year's measurement.
Time frame: 3 year
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