Prospective cohort study investigating the menstrual cycle phase (MCP)-dependent incidence of acute mountain sickness (AMS) in women travelling to 3600 m.
Study Type
OBSERVATIONAL
Enrollment
90
Participants will travel to and stay for 2 days at an altitude of 3600 m.
National Center for Cardiology and Internal Medicine
Bishkek, Gorod Bishkek, Kyrgyzstan
RECRUITINGAcute Mountain Sickness (AMS) Incidence, LLS 2018
MCP-related difference in the AMS incidence. AMS incidence will be defined as a Lake Louise Questionnaire version 2018 score of ≥3.
Time frame: Day 1 to 3 at 3600 m
Acute Mountain Sickness (AMS) Incidence, LLS 1993
MCP-related difference in the AMS incidence. AMS incidence will be defined as a Lake Louise Questionnaire version 1993 score of ≥3.
Time frame: Day 1 to 3 at 3600 m
Acute Mountain Sickness (AMS) Severity, LLS 2018
MCP-related difference on the AMS severity assessed by the Lake Louise Questionnaire version 2018.
Time frame: Day 1 to 3 at 3600 m
Acute Mountain Sickness (AMS) Severity, LLS 1993
MCP-related difference on the AMS severity assessed by the Lake Louise Questionnaire version 1993.
Time frame: Day 1 to 3 at 3600 m
Arterial blood gases
MCP-related difference on the arterial blood gases (pH, PaO2, PaCO2, SaO2).
Time frame: Day 2 at 760 m and day 2 at 3600 m
Hypoxic ventilatory response
MCP-related difference in the hypoxic ventilatory response assessed under FiO2 of 0.115 and while cycling on a bicycle at 30% of predicted maximal work capacity.
Time frame: Day 2 at 760 m
Perceived pain visualization
MCP-related difference on perceived pain sensations, visualized by the SMaRT tablet app
Time frame: Day 1 to 3 at 3600 m
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