Temporomandibular Disorder in Use of Levonorgestrel Intrauterine System

Marmara University100 enrolled

Overview

The goal of this clinical trial is to investigate the possible role of levonorgestrel intrauterine system use(LIU) in the pathogenesis of temporomandibular joint disorder (TMD). In this clinical trial, levonorgestrel intrauterine system patients (n=30) aged 25-50 and control group patients (n=30) with the same demographics and age range are used. The main questions it aims to answer are: To compare the frequency of temporomandibular dysfunction in women using the levonorgestrel intrauterine system with the control group of the same demographic and age range. The levonorgestrel intrauterine system use group consisted of 50 women who had previously a mirena implanted by a gynecologist at least 3 months ago due to menstrual bleeding and pelvic pain. The control group included 50 randomised healthy women who had regular menstrual cycles and were not taking any medication.

Study Type

INTERVENTIONAL

Allocation

NON_RANDOMIZED

Purpose

DIAGNOSTIC

Masking

NONE

Enrollment

100

Conditions

Levonorgestrel Adverse Reaction Temporomandibular Joint Disorders Temporomandibular Disorder

Interventions

Examination of temporomandibular joint and masticator musclesDIAGNOSTIC_TEST

The TMJ and the masticatory muscles were evaluated by the same clinician. Patients described symptoms such as preauricular pain, limited mouth opening, deviation or deflection during mouth opening, and joint sounds. All patients were assessed using Okeson's Muscle and temporomandibular joint examination and treatment outcome form. This form records (for both TMJ) tenderness and pain in the masseter, temporalis, lateral pterygoid, medial pterygoid, sternocleidomastoid, trapezius, splenius capitis, and digastric muscles, as well as maximum interincisal distance, restriction of laterotrusion and protrusive movements, joint sounds, deviation or deflection during mouth opening, and the visual analogue score (VAS) for pain in the TMJ.

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 45 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Being a woman * Having used an intrauterine device for at least 3 months * Being between the ages of 18-50 * Being in American Society of Anesthesiologists-1 and American Society of Anesthesiologists-2 systemic status Exclusion Criteria: * Patients with craniofacial syndrome * Patients with a history of head and neck trauma * Isolated muscle tenderness or previous surgery on TMJ * Patients with rheumatological disorders * Patients with an additional gynecological disease other than endometriosis * Lack of cooperation with the patient.

Outcomes

Primary Outcomes

Evaluation of temporomandibular joint disorder and masticator muscle pain

To measure whether there is any difference in the incidence of temporomandibular joint disorders and masticator muscle pain between two groups.

Time frame: One Day

Central Contacts

Serhat Can, Specialist

CONTACT

+905556161166 drserhatcan@gmail.com

Sinem Busra Kirac Can, Specialist