Previous studies have shown that the spectrum of light influences myopia. LED lights with a partially absent light spectrum increase the risk of myopia progression compared to LEDs with a full spectrum, potentially mediated by the excitability of the parasympathetic nervous system. This study intends to compare pupil size and area, as well as parameters regulated by the autonomic nervous system (such as skin bioelectrical activity and heart rate), between LEDs with a full visible spectrum and LEDs with a partially absent spectrum around 470nm and 730nm. We aim to elucidate the physiological mechanism underlying the effect of light spectrum on pupil changes and myopia.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
SINGLE
Enrollment
66
Subjects will stay in a room with full spectrum light for 5 minutes. After 5 minutes wash-out period, altenate to the other arm.
Subjects will stay in a room with ordinary LED light for 5 minutes. After 5 minutes wash-out period, altenate to the other arm.
pupil size
The pupil diameter is measured in real-time using the Eyelink Portable Duo eye tracker.
Time frame: 5 minutes
Skin conductance response
Rapidly changing and short-duration skin surface potentials measured in real-time using the Biopac MP160 multi-channel physiological recorder.
Time frame: 5 minutes
Respiratory movement
The amplitude of respiratory movements measured in real-time using the Biopac MP160 multi-channel physiological recorder.
Time frame: 5 minutes
Pulse pressure waveform
The amplitude of respiratory movements measured in real-time using the Biopac MP160 multi-channel physiological recorder.
Time frame: 5 minutes
Spherical equivalent refraction
Measured with autorefractor and defined as the sum of spherical power and half of the cylinder power.
Time frame: 5 minutes
Uncorrected visual acuity
Visual acuity without refractive correction.
Time frame: 5 minutes
Axial length
Uncorrected visual acuity: Visual acuity without refractive correction.
Time frame: 5 minutes
Corneal curvature
Anterior corneal curvature measured by the Pentacam corneal topographer
Time frame: 5 minutes
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