A single center pilot trial investigating the feasibility of using actigraphy and salivary melatonin levels to measure the sleep and circadian rhythm of critically ill children aged 3 to 6 years old. This study will also measure the feasibility of providing daytime light exposure as well as restricting all provided nutrition to during daytime hours.
Several of the identified sleep disruptors in a pediatric intensive care environment may not be modifiable, including restricting feeding to daytime hours and providing normal daytime light exposure. This study aims to measure the feasibility of measuring sleep and circadian patterns in a PICU during routine care and during 2 focused sleep promotion interventions: timed daytime light exposure (DLE) and daytime feeding restriction (DFR). The overall objective of this study is to test the hypothesis that, with multi-disciplinary efforts, providing chronotherapeutic care will be feasible and that reliably measuring sleep patterns and the CR of critically ill children with timed salivary melatonin assays and actigraphy is possible.
Study Type
INTERVENTIONAL
Allocation
NON_RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
30
Participants will be exposed to a 10,000 lux light source within 3 feet of their face/eyes to promote the natural circadian rhythm for 2-3 hours from 10am to 12/1pm depending on their nap time at home
Participant's nutrition, parenteral or enteral, will be restricted to the hours when they are normally awake at home.
John R. Oishei Children's Hospital
Buffalo, New York, United States
RECRUITINGFeasibility of monitoring the sleep and circadian rhythm of critically ill children
The number of days that reliable sleep and CR data are obtained using an actigraph and serial salivary melatonin assays
Time frame: PICU Day 1 through 4
Feasibility of providing daytime light exposure
Feasibility will be defined by the percentage of days when DLE was implemented and the average hours of DLE provided using a bedside DLE log
Time frame: PICU Day 2 through 4
Feasibility of restricting nutrition to daytime hours
. The feasibility of daytime restricted feeding will be determined by the percentage of enteral or parenteral nutrition that was provided on each study day outside of the child's daytime feeding period determined by the Intake and Output records in the EMR
Time frame: PICU Day 2 through 4
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.