This study aims to determine the levels of NLRP3, caspase-1 and IL-1β concentrations in the gingival crevicular fluid of paediatric patients with gingivitis and their changes after periodontal treatment.
After being informed about the study and potential risks, necessary periodontal measurements will be performed and gingival crevicular fluid will be collected from all patients who gave written informed consent, and patients with gingivitis will be followed up on the 7th and 30th day after periodontal treatment.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SCREENING
Masking
NONE
Enrollment
60
periodontal therapy
Sultan Keles
Aydin, Turkey (Türkiye)
RECRUITINGNLRP3
NOD-, LRR- and pyrin domain-containing protein 3 level
Time frame: Baseline
Caspase-1
Caspase-1 level
Time frame: Baseline
IL-1 Beta
Interleukin-1 Beta level
Time frame: Baseline
NLRP3
NOD-, LRR- and pyrin domain-containing protein 3 level
Time frame: 7. days - 30. days
Caspase-1
Caspase-1 level
Time frame: 7. days -30. days
IL-1 Beta
Interleukin-1 Beta level
Time frame: 7. days-30. days
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