This study aims to compare the efficacy of different structures of hyaluronic acid, namely cross-linked and non-cross-linked hyaluronic acid, in treating subdeltoid bursitis.
A double-blind, randomized clinical trial will be conducted to collect 52 patients with subdeltoid bursitis. The patients will be injected with cross-linked or non-cross-linked hyaluronic acid under ultrasound guidance. Before treatment, one week after treatment (i.e., one week after injection), one month after treatment, and three months after treatment to detect shoulder pain (visual analog scale; pressure ergometer to measure pain pressure threshold), function (including Disabilities of the Arm, Shoulder, and Hand: DASH and Shoulder Pain and Disability Index: SPADI), quality of life (Brief version of the World Health Organization Quality of Life Scale: WHOQOL-BREF) will be arranged.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
52
cross-linked hyaluronic acid injection with physical therapy
non-cross-linked hyaluronic acid injection with physical therapy
Shin Kong Wu Ho-Su Memorial Hospital
Taipei, Taiwan
Shoulder pain and disability index
measure shoulder pain and disability, ranges from 0-100, higher scores indicate more pain or disability
Time frame: score change from baseline to 1 week, 1 month and 3 months after treatment
Disabilities of the arm, shoulder, and hand
measure sports/music and work related to shoulder pain, ranges from 0-100, higher scores indicate more pain or disability
Time frame: score change from baseline to 1 week, 1 month and 3 months after treatment
Visual analog scale
measure shoulder pain, ranges from 0-10, higher score indicate more pain
Time frame: score change from baseline to 1 week, 1 month and 3 months after treatment
range of motion
measure shoulder range of motion, higher score indicate higher range of motion
Time frame: score change from baseline to 1 week, 1 month and 3 months after treatment
Brief version of the World Health Organization Quality of Life Scale
measure quality of life, ranges from 0-100, higher scores indicate better quality of life
Time frame: score change from baseline to 1 week, 1 month and 3 months after treatment
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