Nutritional Therapy in Patients With Post-extubation Dysphagia

National Institute of Respiratory Diseases, Mexico128 enrolled

Overview

The aim of this study is to evaluate the impact of the prescription of two doses of protein on the amount in kilograms of muscle mass and on the clinical evolution (time until safe swallowing, time until removal of the feeding stoma, number of hospital readmissions, feeding stoma infections, incidence of pneumonia, functionality, number of falls, fractures and mortality) at 6 months after hospital discharge in patients with enteral nutrition due to post-extubation dysphagia.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

DOUBLE

Enrollment

128

Conditions

Dysphagia

Interventions

High protein doseOTHER

High dose of protein (2.0 g/kg) will prescribed for home enteral nutrition

Usual protein doseOTHER

Usual dose of protein (1.5 g/kg) will prescribed for home enteral nutrition

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patients who required invasive mechanical ventilation during their hospital stay with a diagnosis of post-extubation dysphagia diagnosed by fibroendoscopy evaluation of swallowing (FEES). * Patients who discharged with a feeding tube. * Patients with signed informed consent. Exclusion Criteria: * Patients with pre-existing dysphagia, or with neurological conditions that can cause dysphagia (e.g. multiple sclerosis, Parkinson's disease, Alzheimer's, myasthenia gravis). * Patients with chronic kidney disease, defined as a glomerular filtration rate \<60 ml/min. * Patients discharged with a terminal condition and/or life expectancy of less than 3 months. * Diagnosis of HIV, upon receiving clinical follow-up by the team of specialists.

Locations (1)

National Institute of Respiratory Diseases

Mexico City, Mexico

RECRUITING