A Trial of HRS-9813 in Healthy Volunteers

Inclusion Criteria: 1. Understand the study procedures and methods, voluntarily participate in the study, comply with study requirements, and sign the written informed consent form (ICF); 2. Male or female aged 18-55 (adult healthy volunteers); 3. Body mass index (BMI) between 19 and 26 kg/m2; 4. Normal Electrocardiogram (ECG); 5. Men and women of childbearing potential must agree to take effective contraceptive methods. Exclusion Criteria: 1. Any significant acute or chronic medical condition that presents a potential risk to the participant and/or that may compromise the objectives of the study, including active, or history of, urinary stones, urinary tract infection, or intestinal disorder including irritable bowel syndrome; 2. History or presence of malignancy; participants with a history of basal cell or squamous cell carcinoma that has been treated with no evidence of recurrence within 5 years will be allowed for inclusion; 3. Seated systolic blood pressure (SBP) of \<90 mmHg or seated diastolic blood pressure (DBP) of \<60 mmHg; 4. Patients with orthostatic hypotension; 5. Positive results of hepatitis B surface antigen, hepatitis C antibody, syphilis antibody and human immunodeficiency virus antibody.