Texture and Colour Enhancement Imaging in Improving Detection and Miss Rate of Premalignant Lesions

Inclusion Criteria: patients aged 45-85 years and scheduled for screening colonoscopy who provided written informed consent Exclusion Criteria: Surveillance, diagnostic or therapeutic colonoscopy Patients with an already known or suspected colorectal tumour Patients with alarming symptoms and signs, including haematochezia, melena, weight loss or anaemia without specific causes, an abdominal mass and positive digital rectal examination Pregnant or lactating women Patients with gastrointestinal tract obstruction Patients with inflammatory bowel diseases, hereditary CRC syndromes or serrated polyposis syndrome Patients with abnormal blood coagulation or taking antiplatelets or anticoagulants within 7 days before colonoscopy Patients with failed cecal intubation Patients with poor bowel preparation quality that necessitated a second bowel preparation Patients with a history of colonic resection