Effect of Moringa Oleifera Leaves on Glycemic Control of Women With Type 2 Diabetes

University of Milan52 enrolled

Overview

The objective of this clinical trial was to understand whether supplementation of Moringa oleifera leaf powder improved glycemic management in Sahrawi women with type 2 diabetes living in refugee camps. The main question sought to be answered was: \- Does daily supplementation of Moringa oleifera leaf powder, in addition to oral hypoglycemic therapy, improve glycosylated hemoglobin and fasting blood glucose? Researchers compared Moringa supplementation with no Moringa consumption to see if Moringa oleifera worked to improve glycemic control. Participants had to: * Take Moringa oleifera leaves daily or abstain from consuming Moringa for 3 months. * Consistently take prescribed oral hypoglycemic agents * Undergo clinical examinations and measurement of biochemical, metabolic and body composition parameters at the time of recruitment and at the end of the study.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Type 2 Diabetes

Interventions

Women in the experimental group were asked to consistently take the prescribed oral hypoglycemic therapy and to maintain their lifestyle and eating habits. In addition, for the duration of the study (3 months), the experimental group was provided with 10 g of Moringa oleifera leaf powder daily to be consumed with main meals.

Eligibility

Sex: FEMALEMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Diagnosis of type 2 diabetes for at least 1 year * Absence of advanced retinopathy, terminal renal failure, active diabetic ulcers, amputations, and heart failure * Treatment with only oral hypoglycemic drugs. Exclusion Criteria: * Diagnosis of type 1 diabetes * Pregnancy or lactation * Treatment with insulin.

Outcomes

Primary Outcomes

Glycosylated hemoglobin (HbA1c)

Time frame: Glycosylated hemoglobin was measured at recruitment and at the end of the study (three months)

Fasting glucose

Time frame: Fasting glucose was measured at recruitment and at the end of the study (three months)

Secondary Outcomes

BMI

Time frame: BMI were measured at recruitment and at the end of the study (3 months)

Waist circumference

Time frame: Waist circumference were measured at recruitment and at the end of the study (3 months)

Hip circumference

Time frame: Hip circumference were measured at recruitment and at the end of the study (3 months)

% body fat

Time frame: % of body fat were measured at recruitment and at the end of the study (3 months)

Blood pressure

Systolic and diastolic blood pressure

Time frame: Systolic and diastolic blood pressure were measured at recruitment and at the end of the study (3 months)