Effect of Prone Positionning in Non Intubated Patients

Mongi Slim Hospital114 enrolled

Overview

Retrospective single center study on the effect of awake prone positioning in ICU patients with severe hypoxemia related to SARS-COV2

Retrospective, observational study on the effects of awake prone positioning on oxygenation, invasive mechanical ventilation requirement and mortality in non intubation patients with severe hypoxemia related to SARS-COV2 and regardeless of the oxygen supplementation method.

Study Type

OBSERVATIONAL

Enrollment

114

Conditions

SARS-CoV 2 Pneumonia Acute Respiratory Distress Syndrome Prone Positioning

Interventions

Prone positioningPROCEDURE

Prone positioning sessions: at least one session per day proning duration: 2 hours at least per session

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * All adult (\> 18 years) patients, non intubated, with acute respiratory failure due to COVID-19 pulmonary infection Exclusion Criteria: * patients: hemodynamic instability and high doses of vasopressors * patients with contraindications of prone positioning: pregnancy, recent abdominal surgery * patients with pulmonay embolism * patients requiring invasive mechanical ventilation for extra respiratory reasons: neurological failure, urgent surgery

Locations (1)

Mongi Slim hospital

Tunis, Tunisia

Outcomes

Primary Outcomes

Intubation

invasive mechanical ventilation requirement

Time frame: at day 7

Intubation

invasive mechanical ventilation requirement

Time frame: at day 14

Secondary Outcomes

ICU mortality

observed mortality rate in the ICU

Time frame: at Day 14

Data from ClinicalTrials.gov

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