This is a multicentre prospective cohort study where patients will receive up to 14 days of continuous ECG monitoring by wearing a portable monitoring device, starting within 72 hours after noncardiac surgery.
POAF commonly occurs after noncardiac surgery and is associated with adverse long-term outcomes. Despite this, patients with POAF are routinely being missed during clinical practice. Continuous ECG monitoring has the potential to enhance POAF detection and improve clinical care in affected patients. Based on this background, the DETECT-POAF study will determine the incidence of clinically important POAF in those receiving up to 14 days of continuous ECG monitoring within 35 days after noncardiac surgery.
Study Type
OBSERVATIONAL
Enrollment
750
Portable, up to 14 days of monitoring
Hamilton General Hospital
Hamilton, Ontario, Canada
RECRUITINGSt. Joseph's Healthcare Hamilton
Hamilton, Ontario, Canada
NOT_YET_RECRUITINGJuravinski Hospital
Hamilton, Ontario, Canada
Incidence of clinically important post-operative atrial fibrillation/atrial flutter
The primary outcome is clinically important POAF, defined as: 1. Atrial fibrillation (AF) documented by a 12-lead ECG; 2. Confirmed AF (e.g., rhythm strip) that results in symptoms of angina, heart failure, or symptomatic hypotension; 3. Confirmed AF that requires treatment with a rate controlling drug, antiarrhythmic drug, or electrical cardioversion; or, 4. Confirmed continuous AF episode with a minimum duration of 1 hour.
Time frame: Within 35 days of non-cardiac surgery
Incidence of sustained ventricular arrhythmia
Time frame: Within 35 days of non-cardiac surgery
Incidence of sinus node dysfunction
Time frame: Within 35 days of non-cardiac surgery
Incidence of high-grade atrioventricular block
Time frame: Within 35 days of non-cardiac surgery
Incidence of death
Time frame: Within 35 days of non-cardiac surgery
Incidence of clinically important post-operative atrial fibrillation/atrial flutter
Time frame: Within 14 days of continuous cardiac monitoring
Incidence of clinically important post-operative atrial fibrillation/atrial flutter detected by clinical monitoring only
Time frame: Within 35 days of non-cardiac surgery
Incidence of clinically important post-operative atrial fibrillation/atrial flutter define with minimum duration of 6 minutes
Time frame: Within 35 days of non-cardiac surgery
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
London Health Sciences Centre - University Hospital
London, Ontario, Canada
NOT_YET_RECRUITINGNiagara Health System - St. Catharine's Site
St. Catharines, Ontario, Canada
NOT_YET_RECRUITINGHôpital Fleurimont du Centre hospitalier universitaire de Sherbrooke
Sherbrooke, Quebec, Canada
NOT_YET_RECRUITINGIncidence of clinically important post-operative atrial fibrillation/atrial flutter detected by study device monitoring only
Time frame: Within 35 days of non-cardiac surgery
Proportion of participants meeting eligibility criteria for ASPIRE-AF study
Time frame: Within 35 days of non-cardiac surgery
Multivariate odds ratio of risk factors associated with the occurrence of clinically important POAF
A multivariate logistic regression analysis of age, sex, surgical urgency, type of surgery, vascular disease, chronic kidney disease, and heart failure.
Time frame: Within 35 days of non-cardiac surgery