To evaluate the difference among three nerve-sparing techniques(unilateral intrafascial resection, bilateral intrafascial resection, bilateral extrafascial resection) of oncological outcome and functional recovery.
Surgery is a common and effective treatment for localized prostate cancer. The main objective of surgical treatment is to remove the tumor completely in order to achieve the goal of cure. Intrafascial nerve-sparing radical prostatectomy is a radical resection of prostate cancer with minimal damage to the nerves and blood vessels. There are nerves around the prostate that affect sexual function, and damage to these nerves can lead to complications like sexual dysfunction and incontinence. Therefore, how to completely remove the tumor, as far as possible to preserve these nerves, become an important issue in the surgical treatment. This study is aim to evaluate the different among nerve-sparing strategies, including unilateral intrafascial resection, bilateral intrafascial resection and bilateral extrafascial resection, on oncological outcome and functional recovery, so as to provide clinical evidence for nerve-sparing surgery of prostate cancer via robot-assisted posterior approach.
Study Type
OBSERVATIONAL
Enrollment
150
Conducting unilateral intrafascial resection in Retzius-sparing robot-assisted radical prostatectomy
Conducting bilateral intrafascial resection in Retzius-sparing robot-assisted radical prostatectomy
Conducting bilateral extrafascial resection in Retzius-sparing robot-assisted radical prostatectomy
biochemical recurrence-free rates
the rate of patients who do not have biochemical recurrence
Time frame: 3 years
urinary control rate
the rate of patients who do not have incontinence
Time frame: day 0, 3 month, 6 month, 1 year
sexual function
the rate of patients who do not lose sexual function
Time frame: 6 month, 1 year
perioperative complications
the complications that occur in perioperation
Time frame: perioperation
positive rate of incisal margin
the rate of patients who have positive incisal margin after the operation
Time frame: day 0
prostate cancer-specific survival
the survival for prostate cancer
Time frame: 3 years
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