Weaning is Winning? (WeWin Study)

The Hospital for Sick Children120 enrolled

Overview

We propose a multicenter prospective study on pediatric patients with intestinal failure (IF) who weaned off parenteral nutrition (PN).

Children with IF depend on PN. This is associated with frequent and various complications such as metabolic bone disease, micronutrient deficiencies and abnormal body composition. Due to advancements in care, many patients with IF are able to wean off PN; they are so called PN graduates. It is currently not well known how often complications do occur after weaning off PN, and which patients are at highest risk of developing these complications.

Study Type

OBSERVATIONAL

Enrollment

120

Conditions

Intestinal Failure Parenteral Nutrition

Interventions

Weaning off Parenteral NutritionOTHER

pediatric intestinal failure patients who have been weaned off parenteral nutrition

Eligibility

Sex: ALLMin age: 0 YearsMax age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Parenteral Nutrition graduates for at least 1 year, with a history of intestinal failure. * Age \<18 years at time of inclusion. Exclusion criteria: * No consent provided.

Locations (1)

The Hospital for Sick Children

Toronto, Ontario, Canada

RECRUITING

Outcomes

Primary Outcomes

Complications

Assess the frequency of nutritional complications including poor growth, micronutrient deficiencies, poor bone health, abnormal body composition, and delayed pubertal development in PN graduates.

Time frame: From 1 year after weaning off PN to 18 years of age

Data from ClinicalTrials.gov

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