Pain Measured by NRS and EEG in Acute Pulpitis

Cleveland Dental Institute50 enrolled

Overview

The aim of the proposed study is to investigate and comprehensively understand pain perception in patients diagnosed with symptomatic acute pulpitis who are resistant to inferior alveolar nerve block (IANB). The study aims to achieve this by utilizing a dual approach that combines subjective self-reporting of pain intensity using the Numeric Rating Scale (NRS) with objective neurophysiological assessment through brain wave analysis using electroencephalography (EEG). By integrating these two methods, the study seeks to explore potential correlations between self-reported pain scores and neural responses recorded through EEG, providing insights into the pain experience of this specific patient population. Ultimately, the goal of the study is to enhance the understanding of pain perception mechanisms in individuals with symptomatic acute pulpitis resistant to IANB and potentially guide the development of more effective and personalized pain management strategies for these patients.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Acute Pulpitis

Interventions

Brain wave analysis using electroencephalography (EEG).DIAGNOSTIC_TEST

Eligibility

Sex: ALLMin age: 18 YearsMax age: 50 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: Adults aged \[18-50 years\]. Clinically diagnosed with symptomatic acute pulpitis based on dental examination and radiographic findings. Demonstrates resistance to inferior alveolar nerve block (IANB). Willing and able to provide informed consent to participate in the study. Able to communicate effectively in the language used for study procedures. Exclusion Criteria: Individuals with known neurological or psychiatric disorders affecting pain perception. Pregnant individuals or those breastfeeding at the time of the study. History of severe allergies or adverse reactions to local anesthetics or EEG gel. Presence of significant medical conditions that may contraindicate dental procedures or EEG recordings. Individuals taking medications that could significantly affect pain perception (e.g., strong analgesics, sedatives). Any contraindications for dental procedures or EEG recordings as determined by the study's dental and medical professionals. Inability to understand and follow study instructions.

Outcomes

Primary Outcomes

Electroencephalography (EEG)

Changes in alpha brain waves in patients with acute pulpitis and resistant to alveolar nerve block injection

Time frame: 3 months

Numerical Rate Scale (NRS)

Measuring pain perception using NRS (Scale 0-10 where 0 is no pain and 10 is the most unbearable pain) in patients with acute pulpitis and resistant to alveolar nerve block injection.

Time frame: 3 months

Central Contacts

Ahmed I Basyoni

CONTACT

3612290038 a.basyoni@cdiohio.org

Abdelrahman Zaghloul