The main hypothesis is that autonomic dysfunction cannot improve among patients reaching end-stage heart failure. To evaluate this, patients admitted with acute decompensated heart failure in Bispebjerg hospital, and history one or more admissions with the same condition within the prior year, will undergo repeated brief heart monitoring (10 min). Baseline recordings (at admission) will be compared with equivalent measurements before discharge to explore whether heart rate variability increases. Patients will be followed for six months after discharge from the hospital.
If the patient accepts to participate and signed the project informed consent, their clinical record will be followed until the last patient included has been followed for six months.
Study Type
OBSERVATIONAL
Enrollment
200
individual comparison of heart rate variability at admission with a repeated measurement before discharge
Cardiology department Y, Bispebjerg-Frederiksberg Hospital
Frederiksberg, Denmark
RECRUITINGnumber of rehospitalizations
number of emergency rehospitalizations, classified according to: 1. new decompensation of heart failure 2. side effects / complications to therapy for heart failure 3. other
Time frame: up to six months after discharge from index admission
Heart rate Variability change from admission to discharge
Measurement of heart-rate oscillations over a short term (30 min) of continuous three-lead electrocardiogram recording divided into two time domains: Domain 10min: relaxed, supine position for 10 min Domain 30 min: comprising the first 10 min-domain in addition to stand-up and walking for 5 min, followed by sitting relaxed until completing 30 min recording in total
Time frame: repeated measurement at baseline (within 48h from time of index admission) and before discharge (estimated one week on average from index admission)
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