Liver metastases (LM) are common in various types of malignant diseases, either at the diagnosis of the primary tumour or at a later time point. While the resection of colorectal LM (CRLM) is a well-established procedure, with survival rates superior to chemotherapy alone, controversial data still exist on liver resection for non-colorectal LM (NCRLM) (2, 3). These patients comprise a diverse and heterogeneous group usually excluded from surgery due to advanced tumour stage or the presence of concomitant extrahepatic disease. To date, no randomized clinical trial on the surgical treatment of NCRLM has been conducted, and only few retrospective reports are available.The scope of this research project is to develop a large registry of patients undergoing liver surgery for non-colorectal liver metastases.
Study Type
OBSERVATIONAL
Enrollment
300
Resection of non-colorectal liver metastases
Overall Survival
Overall Survival defined as the time elapsed between the date of resective surgery and the date of death for any reason. Patients who are surviving at the end of observation will be considered "censored" at the date of the last available follow-up.
Time frame: From date of enrollment until the date of death from any cause assessed up to 36 months
Disease-free Survival
Disease-free Survival defined as the time from resective surgery to the date of first relapse or last available follow-up, whichever occurs first
Time frame: From date of enrollement until the date of first documented progression assessed up to 36 months
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