Harm Reduction for Smokers With Mental Illness

Dartmouth-Hitchcock Medical Center250 enrolled

Overview

To compare the efficacy of e-cigarette (e-cig) provision with or without behavioral support (SWITCH IT) delivered via telehealth to reduce harm among smokers with MI who cannot quit smoking and are not ready to pursue cessation treatment, and to examine self-regulation (using e-cigs instead of cigarettes to cope with stress/distress and self-efficacy) as a potential mechanism for behavior change from SWITCH IT

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

250

Conditions

Tobacco Dependence

Interventions

SWITCH ITBEHAVIORAL

Behavioral support for switching, 7-10 sessions with SWITCH IT coach delivered during the first 8 weeks of the study. SWITCH IT participants will also have the opportunity to receive supported "field trips" to explore e-cigarette options based on availability, cost, and preferences during week 4 and week 6.

E-cig Provision OnlyOTHER

Provision of e-cigarettes (NJOY) based on combusible use for the first 8 weeks of the study.

Eligibility

Sex: ALLMin age: 21 Years

Medical Language ↔ Plain English

Diagnostic Criteria (must have one to be eligible): * Schizophrenia * Bipolar disorder * Major Depressive Disorders * Posttraumatic disorder * Other anxiety disorders Additional Inclusion Criteria: * 21 years or older; * English-speaking; * Daily smoker (at least 10 cigarettes/day); * At least one quit attempt in the past 5 years using evidence- based pharmacotherapy or behavioral cessation support; * Not currently interested in quitting. Exclusion Criteria: * Currently residing in a nursing home; * Current diagnosis of Asthma; * Cognitive impairment (score \<26 on the Telephone Interview for Cognitive Status (TICS); * Current use of e-cigarettes (\>once a week); * Psychiatric instability (hospitalized in the past month); * Current AND moderate to severe substance use disorder; * Pregnant or planning to become pregnant; * Use of any smoked products other than cigarettes; * Current unstable medical illness making e-cigarette unsafe (e.g., recent heart attack, cancer); * Participation in SWITCH IT pilot study.

Locations (2)

Seven Counties Services

Louisville, Kentucky, United States

RECRUITING

The Providence Center

Providence, Rhode Island, United States

RECRUITING

Outcomes

Primary Outcomes

Change in Urine NNAL

urine levels of NNAL

Time frame: baseline to 8 weeks, 8 weeks to 26 weeeks

Change in CO level

carbon monixide level less than 6

Time frame: baseline to 8 weeks, 8 weeks to 26 weeks

Change in self-reported cigarette use

self-report of combustible cigarette use

Time frame: baseline to 8 weeks 8 weeks to 16 weeks

Central Contacts

Meghan M. Santos, MSW

CONTACT

978-494-4260 meghan.m.santos@hitchcock.org

Gail Williams, MS, MFT

CONTACT

gail.williams@dartmouth.edu

Data from ClinicalTrials.gov

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