Migraine is a neurological disease characterized by moderate or severe headache, associated with nausea, vomiting, and/or sensitivity to light and sound. This study will evaluate the effectiveness of atogepant in treating adult participants with migraine in a real-world setting. Atogepant is an approved drug for preventive treatment of migraine in adults. Approximately 1000 adult participants who are prescribed atogepant by their doctors will be enrolled in this study across the world. Participants will receive atogepant oral tablets as prescribed per standard clinical practice and will be followed for 2 years. There is expected to be no additional burden for participants in this trial. Participants will attend regular visits during the study at a hospital or clinic according to their routine clinical practice.
Study Type
OBSERVATIONAL
Enrollment
1,314
Neurology and Neurodiagnostics of Alabama /ID# 267614
Hoover, Alabama, United States
Rehabilitation & Neurological Services /ID# 267612
Huntsville, Alabama, United States
Barrow Neurological Institute - Dignity Health St. Joseph's Hosp and Medical Ctr /ID# 267610
Phoenix, Arizona, United States
Kenneth Martinez MD, A Medical Corp /ID# 267834
Aliso Viejo, California, United States
BNL Health - Los Angeles Headache Center /ID# 267570
Los Angeles, California, United States
Percentage of Participants Achieving a rating of "much better" or "very much better" as assessed by the Patient Global Impression of Change (PGI-C)
PGI-C is a single item used to measure the patient's impression of overall change in migraine since the first dose of atogepant. The measure uses a 7-point rating scale with responses ranging from "very much better" to "very much worse".
Time frame: Week 12
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Alcanza Clinical Research, LLC /ID# 267838
Lake Mary, Florida, United States
Norton Cancer Institute - St. Matthews /ID# 267605
Louisville, Kentucky, United States
Dent Neurologic Institute - Amherst /ID# 267606
Amherst, New York, United States
Northwell Health - Great Neck /ID# 280705
Great Neck, New York, United States
Northwell Health /ID# 267596
New York, New York, United States
...and 102 more locations