The current study aims to investigate the dynamic serum kisspeptin levels throughout pregnancy and to explore its predictive value for GDM in PCOS.
The current prospective cohort study aims to investigate the dynamic serum kisspeptin levels in the patients with polycystic ovary syndrome (PCOS) at different trimesters of pregnancy, to analyze the associations between serum kisspeptin, insulin, glucose and testosterone, and to explore the predictive value of kisspeptin for GDM and other complications in PCOS patients.
Study Type
OBSERVATIONAL
Enrollment
180
It's a observational cohort study and no interventions are performed.
OB & GYN Hospital of Fudan University
Shanghai, Shanghai Municipality, China
RECRUITINGDynamic changes of serum kisspeptin levels throughout pregnancy in PCOS patients
Serum kisspeptin levels in the first, second trimester and late pregnancy of PCOS patients and control group.
Time frame: 40 weeks
The association between serum Kisspeptin levels and the prevalence of GDM in PCOS patients
The predictive value of serum Kisspeptin levels in the first trimester for GDM in PCOS patients
Time frame: 40 weeks
The association between serum Kisspeptin levels and the prevalence of insulin resistance in PCOS patients
The predictive value of serum Kisspeptin levels in the first trimester for insulin resistance in PCOS patients
Time frame: 40 weeks
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