The Outcomes of Laparoscopic Hybrid Surgery Versus Totally Open Surgery

Changhai Hospital266 enrolled

Overview

Simultaneous colorectal cancer liver metastasis (SCRLM) is one of the risk factors for poor prognosis in colorectal cancer. Surgical resection of primary and metastatic lesions is the first choice of treatment for patients with resectable SCRLM. Simultaneous resection of colorectal cancer liver metastases by totally open surgery (TOS) has been widely used. However, we propose that laparoscopic hybrid surgery (LHS) may have better short and long-term outcomes. This study aimed to compare the safety, short-term, and long-term efficacy of LHS versus TOS for patients with resectable SCRLMs.

Study Type

OBSERVATIONAL

Enrollment

266

Conditions

Resectable Simultaneous Colorectal Cancer Liver Metastasis

Interventions

laparoscopic hybrid surgery (LHS)PROCEDURE

First performed the laparoscopic exploration of the entire abdominal-pelvic cavity to determine the resectability of the primary and metastatic lesions. After the blood vessel detachment and bowel detachment, the distal bowel of the tumor was severed and the pneumoperitoneum was closed. The liver metastases were then removed in both cohorts by open resection through the right subcostal incision.

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: * Liver metastasis was detected while the colorectal cancer was diagnosed. * Both the primary lesions and liver metastases were confirmed by postoperative pathological examination. * Clinical data is complete. Exclusion Criteria: * Patients with unresectable extrahepatic metastases. * Patients with other malignant tumor diseases that have not been cured. * Clinical and pathological data were missed or incomplete follow-up data.

Locations (1)

Department of Colorectal Surgery in Changhai Hospital

Shanghai, Shanghai Municipality, China