Minimally Invasive Non-surgical Therapy With or Without Injectable Bone Putty

Phase 3Not Yet RecruitingNCT06553222

Al-Azhar University30 enrolled

Overview

• All periodontitis patients with infra bony pockets to be included in this study will diagnosed as having stage III periodontitis with probing pocket depth (PPD) ≥ 6 mm, and clinical attachment loss (CAL) ≥ 5mm will be treated by minimally invasive non-surgical therapy or by injectable bone putty

The present study will be designed as a randomized controlled clinical and radiographic. The study will be carried out on stage III grade (B) periodontitis patients with intra-bony defects. Those patients will be selected from the outpatient clinics of the Department of Oral Medicine and Periodontology, Faculty of Dental Medicine, Al-Azhar University, Assiut branch. The study has bee approved by the ethical committee, Faculty of Dental medicine, Al-Azhar University, Assiut branch. 2\. All patients will be fully informed about the study's nature and the possible risks of the study procedures; they sign the consent form before the work.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

SINGLE

Enrollment

Conditions

Periodontal Bone Defects

Interventions

Putty bone - Tricalcium phosphate with Collagen gelBIOLOGICAL

Minimally invasive debridement periodontal flap and Bone graft placement to augment the lost alveolar bone

Eligibility

Sex: ALLMin age: 35 YearsMax age: 55 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * • All periodontitis patients to be included in this study should be diagnosed as having stage III periodontitis with probing pocket depth (PPD) ≥ 6 mm, and clinical attachment loss (CAL) ≥ 5mm. * 2- or 3-wall intra-bony interproximal defect with depth ≥3 mm, a width of ≥3 mm at its most coronal part and 45-55-degree angulation will be selected in order to reduce defect variability * All patients will be free from any systemic diseases according to the American Dental Academy general guidelines for referring dental patients to specialists and other care settings. Exclusion Criteria: • Any patients with any systemic condition that contraindicate any surgical intervention

Outcomes

Primary Outcomes

Primary outcome

measurement (mm) in alveolar bone gain

Time frame: measured at 6 and 12 months postoperative

Data from ClinicalTrials.gov

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