This study aims to explore the clinical effect of THRIVE in improving early postoperative atelectasis in patients undergoing long-term non-intubated anesthesia gastrointestinal endoscopy.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
SUPPORTIVE_CARE
Masking
SINGLE
Enrollment
150
Transnasal humidified rapid insufflation ventilatory exchange(THRIVE)
conventional oxygen mask
Northern Jiangsu People's Hospital
Yangzhou, Jiangsu, China
Incidence of atelectasis
Lung ultrasound examination was performed before anesthesia induction (T1) and immediately after surgery (T2), and patients' modified lung ultrasound score (LUSS) was recorded.
Time frame: Early postoperative period
Diaphragm movement
Time frame: Before anesthesia induction (T1) and immediately after surgery (T2)
Heart rate (HR)
Throughout the procedure, the heart rate (HR) was continuously monitored.
Time frame: Baseline,during surgery and arrived at PACU
Pulse oxygen saturation (SpO2)
Throughout the procedure, the pulse oxygen saturation (SpO2) were continuously monitored.
Time frame: Baseline,during surgery and arrived at PACU
Mean blood pressure (MBP)
Throughout the procedure, the mean blood pressure (MBP) was measured at 3-minute intervals.
Time frame: Baseline,during surgery and arrived at PACU
Patient satisfaction levels
The patients express their satisfaction with procedures on a numerical rating scale, ranging from 0 to 10, where 0 is the minimum and 10 is the maximum satisfaction level.
Time frame: After the patient is awake
Endoscopist satisfaction levels
The Endoscopists express their satisfaction with procedures on a numerical rating scale, ranging from 0 to 10, where 0 is the minimum and 10 is the maximum satisfaction level.
Time frame: After the surgery
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Adverse Events (AEs) During Surgery and PACU
radycardia; Hypertension; Hypotension; Hypoxemia; Aspiration and Regurgitation
Time frame: During surgery and PACU
Adverse Events (AEs) Within 7 Days Post-Operatively
Fever; Cough and Sputum Production; Antibiotic Usage
Time frame: Within 7 days after surgery
PACU Stay Duration
Time frame: The time from entering PACU to improving Aldrete score ≥9
Length of Hospital Stay
Time frame: The time from admission to discharge
Dosage of propofol
Time frame: During surgery
Dosage of remifentanil
Time frame: During surgery