Evaluation of a Predictive Score for the Onset of Moderate to Severe Alcohol Withdrawal Syndrome, the PAWSS, in a Population of Intensive Care Patients at Brest University Hospital

University Hospital, Brest403 enrolled

Overview

alcohol use disorder (AUD) is a very common condition in patients admitting in ICU's. Brutal stop of alcohol consumption may lead to a withdrawal syndrome, wich is associated with a worse outcome for ICU patients (longuer ICU and hospital stays, use of mechanical ventilation, traumas). The aim of this study is to valid a score (PAWSS : prediction of alcohol withdrawal syndrome (AWS) scale) to predict at admission mild to severe AWS in ICU patients population.

Study Type

OBSERVATIONAL

Enrollment

403

Conditions

Alcohol Withdrawal Syndrome

Eligibility

Sex: ALLMin age: 18 YearsMax age: 99 Years

Medical Language ↔ Plain English

Inclusion Criteria: * more than 18 years old * able to answer to PAWSS in the first 48hours of ICU stay Exclusion Criteria: * No alcohol consumption in the last 30 days * hospital stay of more than 5 days at ICU admission * hospital stay less than 5 days in total * expected sedation time of more than 48h * patient not able to understand the PAWSS * no consent

Locations (1)

CHRU Brest

Brest, France

Outcomes

Primary Outcomes

Evaluation of PAWSS statistic performances to predict AWS in ICU patients

Evaluation of sensitivity, specificity, positive and negative predictive values of PAWSS to predict moderate or severe AWS (defined by a CIWA greater than or equal to 8)

Time frame: the first 5 days of hospital stay

Secondary Outcomes

Creation of a new score, the PAWSS-ICU, able to predict AWS in ICU patients

To this end, the characteristics of the \[no weaning/minimal weaning\] and \[moderate weaning/severe weaning\] groups will be compared, in order to identify significant differences between these two groups, and thus enable the creation of a new score. On an exploratory basis : * assess the incidence of alcohol misuse and withdrawal syndrome in our population, * assess the incidence of complications in the population with moderate to severe withdrawal (trauma, occurrence of pneumopathy, need for mechanical ventilation), * assess length of hospital stay and in-hospital mortality. Translated with DeepL.com (free version)

Time frame: during ICU stay