Protocol for Evaluating Physiological and Psychological Adaptation Mechanisms in Tibetan Plateau Environments

N/AEnrolling By InvitationNCT06557928

Peking Union Medical College Hospital17 enrolled

Overview

This study is a single-center prospective observational study. It plans to use a series of physiological and medical instruments and international common physiological and psychological questionnaires. To dynamically detect the changes of physiological and psychological adaptability of doctors in Peking Union Medical College Hospital before leaving Beijing, 1-7 days after arriving at the plateau in Tibet during the acute phase of plateau hypoxic stress, 2 weeks, 3 months, 6 months, 12 months after staying in Tibet during the chronic phase of plateau hypoxic stress, and after returning to Beijing.

Study Type

OBSERVATIONAL

Enrollment

Conditions

High Altitude

Interventions

measurementOTHER

Measurement of multiple physiological indicators and psychological status and multi-omics study

Eligibility

Sex: ALLMin age: 18 YearsMax age: 50 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Healthy individuals aged 20-65 years * They can sign a written informed consent and is willing to cooperate * They have the qualification to aid Tibet and meet the basic requirements of physical examination for aid to Tibet Exclusion Criteria: * Age less than 20 years or more than 65 years * Unable to sign a written informed consent or unwilling to cooperate * They do not have the qualification for supporting Tibet or do not meet the basic requirements of medical examination for supporting Tibet

Outcomes

Primary Outcomes

help understand the physiological mechanisms and psychological changes of hypoxic adaptation

This study is expected to increase our understanding of the physiological mechanisms and psychological changes of hypoxic adaptation mainly through analysis of multi-omics.

Time frame: 2024-5-27~2026-12-1